SYT13

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Synaptotagmin XIII
PDB rendering based on 1wfm.
Available structures: 1wfm
Identifiers
Symbol(s) SYT13; KIAA1427
External IDs OMIM: 607716 MGI: 1933945 HomoloGene: 10823
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 57586 80976
Ensembl ENSG00000019505 ENSMUSG00000027220
Uniprot Q7L8C5 Q9EQT6
Refseq NM_020826 (mRNA)
NP_065877 (protein)		 NM_030725 (mRNA)
NP_109650 (protein)
Location Chr 11: 45.22 - 45.26 Mb Chr 2: 92.72 - 92.76 Mb
Pubmed search [1] [2]

Synaptotagmin XIII, also known as SYT13, is a human gene.[1]

SYT13 belongs to the large synaptotagmin protein family. All synaptotagmins show type I membrane topology, with an extracellular N terminus, a single transmembrane region, and a cytoplasmic C terminus containing tandem C2 domains. Major functions of synaptotagmins include vesicular traffic, exocytosis, and secretion.[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: SYT13 synaptotagmin XIII.

[edit] Further reading

  • Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (1): 65–73. PMID 10718198. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Fukuda M, Mikoshiba K (2001). "Characterization of KIAA1427 protein as an atypical synaptotagmin (Syt XIII).". Biochem. J. 354 (Pt 2): 249–57. PMID 11171101. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166. 
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614. 
  • Craxton M (2001). "Genomic analysis of synaptotagmin genes.". Genomics 77 (1-2): 43–9. doi:10.1006/geno.2001.6619. PMID 11543631. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336. 
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901. 
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