SYT11

From Wikipedia, the free encyclopedia

Synaptotagmin XI

Identifiers

SYT11; DKFZp781D015; KIAA0080; MGC10881; MGC17226; SYT12

External IDs

OMIM: 608741 MGI: 1859547 HomoloGene: 23120

Gene ontology
Molecular Function:	• transporter activity • calcium ion binding
Cellular Component:	• integral to plasma membrane • synaptic vesicle • membrane • synapse
Biological Process:	• transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_152280 (mRNA)
NP_689493 (protein)

XM_981500 (mRNA)
XP_986594 (protein)

Location

Chr 1: 154.1 - 154.12 Mb

n/a

Pubmed search

[1]

[2]

Synaptotagmin XI, also known as SYT11, is a human gene.^[1]

[edit] References

^ Entrez Gene: SYT11 synaptotagmin XI.

[edit] Further reading

Nomura N, Nagase T, Miyajima N, et al. (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 1 (5): 223-9. PMID 7584044.
Mizutani A, Fukuda M, Ibata K, et al. (2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.". J. Biol. Chem. 275 (13): 9823-31. PMID 10734137.
Craxton M (2001). "Genomic analysis of synaptotagmin genes.". Genomics 77 (1-2): 43-9. doi:10.1006/geno.2001.6619. PMID 11543631.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Huynh DP, Scoles DR, Nguyen D, Pulst SM (2004). "The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI.". Hum. Mol. Genet. 12 (20): 2587-97. doi:10.1093/hmg/ddg269. PMID 12925569.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Glass AS, Huynh DP, Franck T, et al. (2004). "Screening for mutations in synaptotagmin XI in Parkinson's disease.". J. Neural Transm. Suppl. (68): 21-8. PMID 15354386.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Inoue S, Imamura A, Okazaki Y, et al. (2007). "Synaptotagmin XI as a candidate gene for susceptibility to schizophrenia.". Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (3): 332-40. doi:10.1002/ajmg.b.30465. PMID 17192956.