Synaptic pharmacology

From Wikipedia, the free encyclopedia

This article is orphaned as few or no other articles link to it. Please help introduce links in articles on related topics. (November 2006)

Synaptic pharmacology is the study of drugs that act on the synapses. It deals with the composition, uses, and effects of drugs that may enhance (receptor) or diminish (blocker) activity at the synapse, which is the junction across which a nerve impulse passes from an axon terminal to a neuron, muscle cell, or gland cell.

A partial list of pharmacological agents that act at synapses follows.

Synaptic pharmacology Channel, Receptor, or Phenomenon Antagonist or Blocker adenosine DCPGX, ZM241385, anoxinine AMPA-R NBQX AMPA-R desensitization cyclothiazide (CTZ) cannabinoid AM-251 GABA-A bicuculline [1], gabazine [2] GABA-B CGP-54626 glycine strychnine kainate R .. metabotropic GluR, broad MCPG [3], pertussis toxin, NEM muscarinic AChR atropine, Scopolamine nicotinic AChR bungarotoxin, curare, DhBe NMDA-R APV