Sym-norspermidine synthase

From Wikipedia, the free encyclopedia

In enzymology, a sym-norspermidine synthase (EC 2.5.1.23) is an enzyme that catalyzes the chemical reaction

S-adenosylmethioninamine + propane-1,3-diamine 5'-methylthioadenosine + bis(3-aminopropyl)amine

Thus, the two substrates of this enzyme are S-adenosylmethioninamine and propane-1,3-diamine, whereas its two products are 5'-methylthioadenosine and bis(3-aminopropyl)amine.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase. This enzyme participates in urea cycle and metabolism of amino groups.

[edit] References

• IUBMB entry for 2.5.1.23
• BRENDA references for 2.5.1.23 (Recommended.)
• PubMed references for 2.5.1.23
• PubMed Central references for 2.5.1.23
• Google Scholar references for 2.5.1.23
• Aleksijevic A, Grove J, Schuber F (1979). "Studies on polyamine biosynthesis in Euglena gracilis". Biochim. Biophys. Acta. 565: 199–207. PMID 116684. 
• Villanueva VR, Adlakha RC and Calbayrac R (1980). "Biosynthesis of polyamines in Euglena gracilis". Phytochemistry 19: 787–790. doi:10.1016/0031-9422(80)85111-9. 

[edit] External links

• IUBMB entry for 2.5.1.23

• KEGG entry for 2.5.1.23

• BRENDA entry for 2.5.1.23

• NiceZyme view of 2.5.1.23

• EC2PDB: PDB structures for 2.5.1.23

• PRIAM entry for 2.5.1.23

• PUMA2 entry for 2.5.1.23

• IntEnz: Integrated Enzyme entry for 2.5.1.23

• MetaCyc entry for 2.5.1.23

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050314: sym-norspermidine synthase

• AMIGO entry for GO code 0050314: sym-norspermidine synthase