SYCP1

From Wikipedia, the free encyclopedia

Synaptonemal complex protein 1

Identifiers

SYCP1; HOM-TES-14; MGC104417; SCP1

External IDs

OMIM: 602162 MGI: 105931 HomoloGene: 2389

Gene ontology
Molecular Function:	• DNA binding • protein binding
Cellular Component:	• synaptonemal complex • lateral element • central element • transverse filament • nucleus
Biological Process:	• cell cycle • meiosis • synaptonemal complex assembly • meiotic recombination • spermatogenesis • cell division

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003176 (mRNA)
NP_003167 (protein)

NM_011516 (mRNA)
NP_035646 (protein)

Location

Chr 1: 115.2 - 115.34 Mb

Chr 3: 102.97 - 103.06 Mb

Pubmed search

[1]

[2]

Synaptonemal complex protein 1, also known as SYCP1, is a human gene.^[1]

[edit] References

^ Entrez Gene: SYCP1 synaptonemal complex protein 1.

[edit] Further reading

Neumann F, Wagner C, Preuss KD, et al. (2005). "Identification of an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4+ T cells.". Blood 106 (9): 3105-13. doi:10.1182/blood-2005-04-1487. PMID 16030183.
Costa Y, Speed R, Ollinger R, et al. (2005). "Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the centre of meiosis.". J. Cell. Sci. 118 (Pt 12): 2755-62. doi:10.1242/jcs.02402. PMID 15944401.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Eichmuller S, Usener D, Dummer R, et al. (2001). "Serological detection of cutaneous T-cell lymphoma-associated antigens.". Proc. Natl. Acad. Sci. U.S.A. 98 (2): 629-34. doi:10.1073/pnas.021386498. PMID 11149944.
Türeci O, Sahin U, Zwick C, et al. (1998). "Identification of a meiosis-specific protein as a member of the class of cancer/testis antigens.". Proc. Natl. Acad. Sci. U.S.A. 95 (9): 5211-6. PMID 9560255.
Kondoh N, Nishina Y, Tsuchida J, et al. (1997). "Assignment of synaptonemal complex protein 1 (SCP1) to human chromosome 1p13 by fluorescence in situ hybridization and its expression in the testis.". Cytogenet. Cell Genet. 78 (2): 103-4. PMID 9371398.
Meuwissen RL, Meerts I, Hoovers JM, et al. (1997). "Human synaptonemal complex protein 1 (SCP1): isolation and characterization of the cDNA and chromosomal localization of the gene.". Genomics 39 (3): 377-84. doi:10.1006/geno.1996.4373. PMID 9119375.
Meuwissen RL, Offenberg HH, Dietrich AJ, et al. (1993). "A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes.". EMBO J. 11 (13): 5091-100. PMID 1464329.