Survival of motor neuron
From Wikipedia, the free encyclopedia
Identifiers | |
Symbol | SMN1 |
Alt. Symbols | SMA@, SMA |
Entrez | 6606 |
HUGO | 11117 |
OMIM | 600354 |
RefSeq | NM_000344 |
UniProt | Q16637 |
Other data | |
Locus | Chr. 5 q13 |
survival of motor neuron 2, centromeric
|
|
Identifiers | |
Symbol | SMN2 |
Entrez | 6607 |
HUGO | 11118 |
OMIM | 601627 |
RefSeq | NM_017411 |
UniProt | Q16637 |
Other data | |
Locus | Chr. 5 q13 |
Survival of motor neuron is a protein associated with spinal muscular atrophy.
A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1]
[edit] See also
[edit] References
- ^ Lunn MR, Root DE, Martino AM, et al (2004). "Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism". Chem Biol 11 (11): 1489–93. doi: . PMID 15555999.