Survival of motor neuron

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Identifiers
Symbol SMN1
Alt. Symbols SMA@, SMA
Entrez 6606
HUGO 11117
OMIM 600354
RefSeq NM_000344
UniProt Q16637
Other data
Locus Chr. 5 q13
survival of motor neuron 2, centromeric
Identifiers
Symbol SMN2
Entrez 6607
HUGO 11118
OMIM 601627
RefSeq NM_017411
UniProt Q16637
Other data
Locus Chr. 5 q13

Survival of motor neuron is a protein associated with spinal muscular atrophy.

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1]

[edit] See also

[edit] References

  1. ^ Lunn MR, Root DE, Martino AM, et al (2004). "Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism". Chem Biol 11 (11): 1489–93. doi:10.1016/j.chembiol.2004.08.024. PMID 15555999. 

[edit] External links