Sulfapyridine
From Wikipedia, the free encyclopedia
Sulfapyridine
|
|
Systematic (IUPAC) name | |
4-amino-N-pyridin-2-ylbenzenesulfonamide | |
Identifiers | |
CAS number | |
ATC code | J01 |
PubChem | |
Chemical data | |
Formula | C11H11N3O2S |
Mol. mass | 249.29 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | ? |
| Original laboratory code: M&B 693. Sulfapyridine is a sulfonamide antibacterial. Along with mesalamine, it forms the drug sulfasalazine.
|
Discovered by May & Baker Ltd and logged in their Test Book on 2 November 1937 under Code No M&B693. Successfully used to treat Winston Churchill's bacterial pneumonia in 1942. In a subsequent radio broadcast he said "This admirable M&B from which I did not suffer any inconvenience, was used at the earliest moment and, after a week's fever, the intruders were repulsed." In 1944 M&B693 also saved Nero, the Royal Circus lion, from pneumonia.[Glasgow Evening News January 1944.]