SUDS3

From Wikipedia, the free encyclopedia

Suppressor of defective silencing 3 homolog (S. cerevisiae)

Identifiers

SUDS3; FLJ00052; MGC104711; SAP45; SDS3

External IDs

OMIM: 608250 MGI: 1919204 HomoloGene: 15906

Gene ontology
Molecular Function:	• protein binding • histone deacetylase binding
Cellular Component:	• Sin3 complex
Biological Process:	• transcription • regulation of transcription, DNA-dependent • negative regulation of transcription • chromatin modification

Orthologs

Human

Mouse

Refseq

NM_022491 (mRNA)
NP_071936 (protein)

NM_178622 (mRNA)
NP_848737 (protein)

Location

Chr 12: 117.3 - 117.34 Mb

Chr 5: 117.35 - 117.38 Mb

Pubmed search

[1]

[2]

Suppressor of defective silencing 3 homolog (S. cerevisiae), also known as SUDS3, is a human gene.^[1]

SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae).

[edit] Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Fleischer TC, Yun UJ, Ayer DE (2003). "Identification and characterization of three new components of the mSin3A corepressor complex.". Mol. Cell. Biol. 23 (10): 3456-67. PMID 12724404.
Wysocka J, Myers MP, Laherty CD, et al. (2003). "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.". Genes Dev. 17 (7): 896-911. doi:10.1101/gad.252103. PMID 12670868.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Alland L, David G, Shen-Li H, et al. (2002). "Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex.". Mol. Cell. Biol. 22 (8): 2743-50. PMID 11909966.
Hattori A, Okumura K, Nagase T, et al. (2001). "Characterization of long cDNA clones from human adult spleen.". DNA Res. 7 (6): 357-66. PMID 11214971.