Sucrose synthase

From Wikipedia, the free encyclopedia

In enzymology, a sucrose synthase (EC 2.4.1.13) is an enzyme that catalyzes the chemical reaction

NDP-glucose + D-fructose $\rightleftharpoons$ NDP + sucrose

Thus, the two substrates of this enzyme are NDP-glucose and D-fructose, whereas its two products are NDP and sucrose.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase. Other names in common use include UDPglucose-fructose glucosyltransferase, sucrose synthetase, sucrose-UDP glucosyltransferase, sucrose-uridine diphosphate glucosyltransferase, and uridine diphosphoglucose-fructose glucosyltransferase. This enzyme participates in starch and sucrose metabolism.

[edit] References

IUBMB entry for 2.4.1.13
BRENDA references for 2.4.1.13 (Recommended.)
PubMed references for 2.4.1.13
PubMed Central references for 2.4.1.13
Google Scholar references for 2.4.1.13
Avigad G and Milner Y (1966). "UDP-glucose:fructose transglucosylase from sugar beet roots". Methods Enzymol. 8: 341–345.
CARDINI CE, LELOIR LF, CHIRIBOGA J (1955). "The biosynthesis of sucrose". J. Biol. Chem. 214: 149–55. PMID 14367373.
Delmer DP (1972). "The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings". J. Biol. Chem. 247: 3822–8. PMID 4624446.
Murata T, Sugiyama T, Minamikawa T, Akazawa T (1966). "Enzymic mechanism of starch synthesis in ripening rice grains. 3 Mechanism of the sucrose-starch conversion". Arch. Biochem. Biophys. 113: 34–44. PMID 5941994.
Yoshinaga F, Mori H, Sakai F, Hayashi T (1998). "An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11". Plant. Cell. Physiol. 39: 1337–41. PMID 10050318.
Porchia AC, Curatti L, Salerno GL (1999). "Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence". Planta. 210: 34–40. PMID 10592030.
Ross, HA and Davies HV (1992). "Purification and characterization of sucrose synthase from the cotyledons of Vicia fava L". Plant Physiol. 100: 1008–1013.
Silvius JE and Snyder FW (1979). "Comparative enzymic studies of sucrose metabolism in the taproots and fibrous roots of Beta vulgaris L". Plant Physiol. 64: 1070–1073.
Tanase K, Yamaki S (2000). "Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit". Plant. Cell. Physiol. 41: 408–14. PMID 10845453.
T, Pozueta-Romero J (2003). "Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants". Plant. Cell. Physiol. 44: 500–9. PMID 12773636.