Succinyldiaminopimelate transaminase

From Wikipedia, the free encyclopedia

In enzymology, a succinyldiaminopimelate transaminase (EC 2.6.1.17) is an enzyme that catalyzes the chemical reaction

N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate N-succinyl-L-2-amino-6-oxoheptanedioate + L-glutamate

Thus, the two substrates of this enzyme are N-succinyl-L-2,6-diaminoheptanedioate and 2-oxoglutarate, whereas its two products are N-succinyl-L-2-amino-6-oxoheptanedioate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase. Other names in common use include succinyldiaminopimelate aminotransferase, and N-succinyl-L-diaminopimelic glutamic transaminase. This enzyme participates in lysine biosynthesis. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 2.6.1.17
• BRENDA references for 2.6.1.17 (Recommended.)
• PubMed references for 2.6.1.17
• PubMed Central references for 2.6.1.17
• Google Scholar references for 2.6.1.17
• Peterkofsky B and Gilvarg C (1961). "N-Succinyl-L-diaminopimelic-glutamic transaminase". J. Biol. Chem. 236: 1432–1438. 

[edit] External links

The CAS registry number for this enzyme class is 9030-46-0.

• IUBMB entry for 2.6.1.17

• KEGG entry for 2.6.1.17

• BRENDA entry for 2.6.1.17

• NiceZyme view of 2.6.1.17

• EC2PDB: PDB structures for 2.6.1.17

• PRIAM entry for 2.6.1.17

• PUMA2 entry for 2.6.1.17

• IntEnz: Integrated Enzyme entry for 2.6.1.17

• MetaCyc entry for 2.6.1.17

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0009016: succinyldiaminopimelate transaminase

• AMIGO entry for GO code 0009016: succinyldiaminopimelate transaminase