Succinyl-diaminopimelate desuccinylase

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In enzymology, a succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) is an enzyme that catalyzes the chemical reaction

N-succinyl-LL-2,6-diaminoheptanedioate + H₂O succinate + LL-2,6-diaminoheptanedioate

Thus, the two substrates of this enzyme are N-succinyl-LL-2,6-diaminoheptanedioate and H₂O, whereas its two products are succinate and LL-2,6-diaminoheptanedioate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase. This enzyme is also called N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase. This enzyme participates in lysine biosynthesis.

[edit] References

• IUBMB entry for 3.5.1.18
• BRENDA references for 3.5.1.18 (Recommended.)
• PubMed references for 3.5.1.18
• PubMed Central references for 3.5.1.18
• Google Scholar references for 3.5.1.18
• Kindler SH and Gilvarg C (1960). "N-Succinyl-L-2,6-diaminopimelic acid deacylase". J. Biol. Chem. 235: 3532–3535. 

[edit] External links

The CAS registry number for this enzyme class is 9024-94-6.

• IUBMB entry for 3.5.1.18

• KEGG entry for 3.5.1.18

• BRENDA entry for 3.5.1.18

• NiceZyme view of 3.5.1.18

• EC2PDB: PDB structures for 3.5.1.18

• PRIAM entry for 3.5.1.18

• PUMA2 entry for 3.5.1.18

• IntEnz: Integrated Enzyme entry for 3.5.1.18

• MetaCyc entry for 3.5.1.18

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0009014: succinyl-diaminopimelate desuccinylase

• AMIGO entry for GO code 0009014: succinyl-diaminopimelate desuccinylase