Succinyl-CoA hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a succinyl-CoA hydrolase (EC 3.1.2.3) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + H₂O CoA + succinate

Thus, the two substrates of this enzyme are succinyl-CoA and H₂O, whereas its two products are CoA and succinate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is succinyl-CoA hydrolase. Other names in common use include succinyl-CoA acylase, succinyl coenzyme A hydrolase, and succinyl coenzyme A deacylase. This enzyme participates in citrate cycle (tca cycle).

[edit] References

• IUBMB entry for 3.1.2.3
• BRENDA references for 3.1.2.3 (Recommended.)
• PubMed references for 3.1.2.3
• PubMed Central references for 3.1.2.3
• Google Scholar references for 3.1.2.3
• Gergely J, Hele P and Ramakrishnan CV (1952). "Succinyl and acetyl coenzyme A deacylases". J. Biol. Chem. 198: 323–334. 

[edit] External links

The CAS registry number for this enzyme class is 9025-86-9.

• IUBMB entry for 3.1.2.3

• KEGG entry for 3.1.2.3

• BRENDA entry for 3.1.2.3

• NiceZyme view of 3.1.2.3

• EC2PDB: PDB structures for 3.1.2.3

• PRIAM entry for 3.1.2.3

• PUMA2 entry for 3.1.2.3

• IntEnz: Integrated Enzyme entry for 3.1.2.3

• MetaCyc entry for 3.1.2.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004778: succinyl-CoA hydrolase

• AMIGO entry for GO code 0004778: succinyl-CoA hydrolase