SUCLG1

From Wikipedia, the free encyclopedia

Succinate-CoA ligase, GDP-forming, alpha subunit

PDB rendering based on 1euc.

Available structures: 1euc, 1eud, 2fp4, 2fpg, 2fpi, 2fpp

Identifiers

Symbol(s)

SUCLG1; FLJ21114; SUCLA1

External IDs

MGI: 1927234 HomoloGene: 55785

Gene ontology
Molecular Function:	• nucleotide binding • succinate-CoA ligase (GDP-forming) activity • GTP binding • ligase activity
Cellular Component:	• mitochondrion • mitochondrial inner membrane
Biological Process:	• tricarboxylic acid cycle • metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003849 (mRNA)
NP_003840 (protein)

NM_019879 (mRNA)
NP_063932 (protein)

Location

Chr 2: 84.5 - 84.54 Mb

Chr 6: 73.18 - 73.21 Mb

Pubmed search

[1]

[2]

Succinate-CoA ligase, GDP-forming, alpha subunit, also known as SUCLG1, is a human gene.^[1]

[edit] References

^ Entrez Gene: SUCLG1 succinate-CoA ligase, GDP-forming, alpha subunit.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
James M, Man NT, Edwards YH, Morris GE (1997). "The molecular basis for cross-reaction of an anti-dystrophin antibody with alpha-actinin.". Biochim. Biophys. Acta 1360 (2): 169–76. PMID 9128182.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Fraser ME, James MN, Bridger WA, Wolodko WT (2000). "Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase.". J. Mol. Biol. 299 (5): 1325–39. doi:10.1006/jmbi.2000.3807. PMID 10873456.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Tsang HT, Connell JW, Brown SE, et al. (2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.". Genomics 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003. PMID 16730941.
Ostergaard E, Christensen E, Kristensen E, et al. (2007). "Deficiency of the alpha subunit of succinate-coenzyme A ligase causes fatal infantile lactic acidosis with mitochondrial DNA depletion.". Am. J. Hum. Genet. 81 (2): 383–7. doi:10.1086/519222. PMID 17668387.