STX8

From Wikipedia, the free encyclopedia


Syntaxin 8
PDB rendering based on 1gl2.
Available structures: 1gl2
Identifiers
Symbol(s) STX8; CARB
External IDs OMIM: 604203 MGI: 1890156 HomoloGene: 37973
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9482 55943
Ensembl ENSG00000170310 ENSMUSG00000020903
Uniprot Q9UNK0 Q5F234
Refseq NM_004853 (mRNA)
NP_004844 (protein)		 XM_001002438 (mRNA)
XP_001002438 (protein)
Location Chr 17: 9.09 - 9.42 Mb Chr 11: 67.78 - 68.02 Mb
Pubmed search [1] [2]

Syntaxin 8, also known as STX8, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: STX8 syntaxin 8.

[edit] Further reading

  • Steegmaier M, Yang B, Yoo JS, et al. (1999). "Three novel proteins of the syntaxin/SNAP-25 family.". J. Biol. Chem. 273 (51): 34171–9. PMID 9852078. 
  • Thoreau V, Bergès T, Callebaut I, et al. (1999). "Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8).". Biochem. Biophys. Res. Commun. 257 (2): 577–83. doi:10.1006/bbrc.1999.0503. PMID 10198254. 
  • Prekeris R, Yang B, Oorschot V, et al. (1999). "Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking.". Mol. Biol. Cell 10 (11): 3891–908. PMID 10564279. 
  • Subramaniam VN, Loh E, Horstmann H, et al. (2000). "Preferential association of syntaxin 8 with the early endosome.". J. Cell. Sci. 113 ( Pt 6): 997–1008. PMID 10683148. 
  • McShea A, Samuel T, Eppel JT, et al. (2000). "Identification of CIP-1-associated regulator of cyclin B (CARB), a novel p21-binding protein acting in the G2 phase of the cell cycle.". J. Biol. Chem. 275 (30): 23181–6. doi:10.1074/jbc.M001772200. PMID 10781590. 
  • Scales SJ, Chen YA, Yoo BY, et al. (2000). "SNAREs contribute to the specificity of membrane fusion.". Neuron 26 (2): 457–64. PMID 10839363. 
  • Antonin W, Holroyd C, Fasshauer D, et al. (2001). "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function.". EMBO J. 19 (23): 6453–64. doi:10.1093/emboj/19.23.6453. PMID 11101518. 
  • Wade N, Bryant NJ, Connolly LM, et al. (2001). "Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells.". J. Biol. Chem. 276 (23): 19820–7. doi:10.1074/jbc.M010838200. PMID 11278762. 
  • Antonin W, Fasshauer D, Becker S, et al. (2002). "Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs.". Nat. Struct. Biol. 9 (2): 107–11. doi:10.1038/nsb746. PMID 11786915. 
  • Bogdanovic A, Bennett N, Kieffer S, et al. (2002). "Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.". Biochem. J. 368 (Pt 1): 29–39. doi:10.1042/BJ20020845. PMID 12175335. 
  • Xu Y, Martin S, James DE, Hong W (2003). "GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus.". Mol. Biol. Cell 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMID 12388752. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Kim BY, Ueda M, Kominami E, et al. (2004). "Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex.". Biochem. Biophys. Res. Commun. 311 (3): 577–82. PMID 14623309. 
  • Zhu X, McShea A, Harris PL, et al. (2004). "Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease.". J. Neurosci. Res. 75 (5): 698–703. doi:10.1002/jnr.20028. PMID 14991845. 
  • Bilan F, Thoreau V, Nacfer M, et al. (2005). "Syntaxin 8 impairs trafficking of cystic fibrosis transmembrane conductance regulator (CFTR) and inhibits its channel activity.". J. Cell. Sci. 117 (Pt 10): 1923–35. doi:10.1242/jcs.01070. PMID 15039462. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
 This article on a gene on chromosome 17 is a stub. You can help Wikipedia by expanding it.