STX7

From Wikipedia, the free encyclopedia

Syntaxin 7

PDB rendering based on 1gl2.

Available structures: 1gl2

Identifiers

Symbol(s)

STX7;

External IDs

OMIM: 603217 MGI: 1858210 HomoloGene: 37823

Gene ontology
Molecular Function:	• protein binding • protein transporter activity
Cellular Component:	• endosome • integral to plasma membrane • membrane
Biological Process:	• intracellular protein transport • post-Golgi vesicle-mediated transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003569 (mRNA)
NP_003560 (protein)

NM_016797 (mRNA)
NP_058077 (protein)

Location

Chr 6: 132.82 - 132.88 Mb

Chr 10: 23.84 - 23.88 Mb

Pubmed search

[1]

[2]

Syntaxin 7, also known as STX7, is a human gene.^[1]

[edit] References

^ Entrez Gene: STX7 syntaxin 7.

[edit] Further reading

Wang H, Frelin L, Pevsner J (1997). "Human syntaxin 7: a Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes.". Gene 199 (1-2): 39-48. PMID 9358037.
Wong SH, Xu Y, Zhang T, Hong W (1998). "Syntaxin 7, a novel syntaxin member associated with the early endosomal compartment.". J. Biol. Chem. 273 (1): 375-80. PMID 9417091.
Steegmaier M, Yang B, Yoo JS, et al. (1999). "Three novel proteins of the syntaxin/SNAP-25 family.". J. Biol. Chem. 273 (51): 34171-9. PMID 9852078.
Prekeris R, Yang B, Oorschot V, et al. (1999). "Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking.". Mol. Biol. Cell 10 (11): 3891-908. PMID 10564279.
Nakamura N, Yamamoto A, Wada Y, Futai M (2000). "Syntaxin 7 mediates endocytic trafficking to late endosomes.". J. Biol. Chem. 275 (9): 6523-9. PMID 10692457.
Scales SJ, Chen YA, Yoo BY, et al. (2000). "SNAREs contribute to the specificity of membrane fusion.". Neuron 26 (2): 457-64. PMID 10839363.
Mullock BM, Smith CW, Ihrke G, et al. (2000). "Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and Is required for late endosome-lysosome fusion.". Mol. Biol. Cell 11 (9): 3137-53. PMID 10982406.
Antonin W, Holroyd C, Fasshauer D, et al. (2001). "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function.". EMBO J. 19 (23): 6453-64. doi:10.1093/emboj/19.23.6453. PMID 11101518.
Wade N, Bryant NJ, Connolly LM, et al. (2001). "Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells.". J. Biol. Chem. 276 (23): 19820-7. doi:10.1074/jbc.M010838200. PMID 11278762.
Kim BY, Krämer H, Yamamoto A, et al. (2001). "Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7.". J. Biol. Chem. 276 (31): 29393-402. doi:10.1074/jbc.M101778200. PMID 11382755.
Rotem-Yehudar R, Galperin E, Horowitz M (2001). "Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29.". J. Biol. Chem. 276 (35): 33054-60. doi:10.1074/jbc.M009913200. PMID 11423532.
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs.". Genome Res. 11 (10): 1758-65. doi:10.1101/gr.180101. PMID 11591653.
Antonin W, Fasshauer D, Becker S, et al. (2002). "Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs.". Nat. Struct. Biol. 9 (2): 107-11. doi:10.1038/nsb746. PMID 11786915.
Antonin W, Dulubova I, Arac D, et al. (2002). "The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly.". J. Biol. Chem. 277 (39): 36449-56. doi:10.1074/jbc.M204369200. PMID 12114520.
Bogdanovic A, Bennett N, Kieffer S, et al. (2002). "Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.". Biochem. J. 368 (Pt 1): 29-39. doi:10.1042/BJ20020845. PMID 12175335.
Collins RF, Schreiber AD, Grinstein S, Trimble WS (2002). "Syntaxins 13 and 7 function at distinct steps during phagocytosis.". J. Immunol. 169 (6): 3250-6. PMID 12218144.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Adkins JN, Varnum SM, Auberry KJ, et al. (2003). "Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.". Mol. Cell Proteomics 1 (12): 947-55. PMID 12543931.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566-9. doi:10.1038/nbt810. PMID 12665801.
Suzuki J, Ohnishi H, Wada A, et al. (2003). "Involvement of syntaxin 7 in human gastric epithelial cell vacuolation induced by the Helicobacter pylori-produced cytotoxin VacA.". J. Biol. Chem. 278 (28): 25585-90. doi:10.1074/jbc.M212445200. PMID 12730232.