STX12

From Wikipedia, the free encyclopedia

Syntaxin 12

PDB rendering based on 2dnx.

Available structures: 2dnx, 2nps

Identifiers

Symbol(s)

STX12; MGC51957; STX13; STX14

External IDs

OMIM: 606892 MGI: 1931027 HomoloGene: 41508

Gene ontology
Molecular Function:	• protein transporter activity
Cellular Component:	• membrane • integral to membrane
Biological Process:	• intracellular protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_177424 (mRNA)
NP_803173 (protein)

NM_133887 (mRNA)
NP_598648 (protein)

Location

Chr 1: 27.97 - 28.02 Mb

Chr 4: 132.13 - 132.16 Mb

Pubmed search

[1]

[2]

Syntaxin 12, also known as STX12, is a human gene.^[1]

[edit] References

^ Entrez Gene: STX12 syntaxin 12.

[edit] Further reading

Falcón-Pérez JM, Dell'Angelica EC (2002). "The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis.". Pigment Cell Res. 15 (2): 82–6. PMID 11936273.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.
Tang BL, Tan AE, Lim LK, et al. (1998). "Syntaxin 12, a member of the syntaxin family localized to the endosome.". J. Biol. Chem. 273 (12): 6944–50. PMID 9507000.
Advani RJ, Bae HR, Bock JB, et al. (1998). "Seven novel mammalian SNARE proteins localize to distinct membrane compartments.". J. Biol. Chem. 273 (17): 10317–24. PMID 9553086.
Prekeris R, Klumperman J, Chen YA, Scheller RH (1998). "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes.". J. Cell Biol. 143 (4): 957–71. PMID 9817754.
Steegmaier M, Yang B, Yoo JS, et al. (1999). "Three novel proteins of the syntaxin/SNAP-25 family.". J. Biol. Chem. 273 (51): 34171–9. PMID 9852078.
McBride HM, Rybin V, Murphy C, et al. (1999). "Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13.". Cell 98 (3): 377–86. PMID 10458612.
Huang L, Kuo YM, Gitschier J (1999). "The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency.". Nat. Genet. 23 (3): 329–32. doi:10.1038/15507. PMID 10610180.
Minakami R, Kato A, Sugiyama H (2000). "Interaction of Vesl-1L/Homer 1c with syntaxin 13.". Biochem. Biophys. Res. Commun. 272 (2): 466–71. doi:10.1006/bbrc.2000.2777. PMID 10833436.
Hirling H, Steiner P, Chaperon C, et al. (2000). "Syntaxin 13 is a developmentally regulated SNARE involved in neurite outgrowth and endosomal trafficking.". Eur. J. Neurosci. 12 (6): 1913–23. PMID 10886332.
Steiner P, Sarria JC, Glauser L, et al. (2002). "Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD.". J. Cell Biol. 157 (7): 1197–209. doi:10.1083/jcb.200202022. PMID 12070131.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Sun W, Yan Q, Vida TA, Bean AJ (2003). "Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complex.". J. Cell Biol. 162 (1): 125–37. doi:10.1083/jcb.200302083. PMID 12847087.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Bared SM, Buechler C, Boettcher A, et al. (2005). "Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells.". Mol. Biol. Cell 15 (12): 5399–407. doi:10.1091/mbc.E04-03-0182. PMID 15469992.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.