Strombine dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a strombine dehydrogenase (EC 1.5.1.22) is an enzyme that catalyzes the chemical reaction

N-(carboxymethyl)-D-alanine + NAD⁺ + H₂O glycine + pyruvate + NADH + H⁺

The 3 substrates of this enzyme are N-(carboxymethyl)-D-alanine, NAD⁺, and H₂O, whereas its 4 products are glycine, pyruvate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming). Other names in common use include strombine[N-(carboxymethyl)-D-alanine]dehydrogenase, and N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase.

[edit] References

• IUBMB entry for 1.5.1.22
• BRENDA references for 1.5.1.22 (Recommended.)
• PubMed references for 1.5.1.22
• PubMed Central references for 1.5.1.22
• Google Scholar references for 1.5.1.22
• Dando PR (1981). "Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine dehydrogenase from the mussel Mytilus edulis L". Biochem. Soc. Trans. 9: 297–298. 

[edit] External links

The CAS registry number for this enzyme class is 79393-84-3.

• IUBMB entry for 1.5.1.22

• KEGG entry for 1.5.1.22

• BRENDA entry for 1.5.1.22

• NiceZyme view of 1.5.1.22

• EC2PDB: PDB structures for 1.5.1.22

• PRIAM entry for 1.5.1.22

• PUMA2 entry for 1.5.1.22

• IntEnz: Integrated Enzyme entry for 1.5.1.22

• MetaCyc entry for 1.5.1.22

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050305: strombine dehydrogenase

• AMIGO entry for GO code 0050305: strombine dehydrogenase