Streptomycin 3"-adenylyltransferase

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In enzymology, a streptomycin 3"-adenylyltransferase (EC 2.7.7.47) is an enzyme that catalyzes the chemical reaction

ATP + streptomycin diphosphate + 3"-adenylylstreptomycin

Thus, the two substrates of this enzyme are ATP and streptomycin, whereas its two products are diphosphate and [[3-adenylylstreptomycin]].

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:streptomycin 3"-adenylyltransferase. Other names in common use include streptomycin adenylate synthetase, streptomycin adenyltransferase, streptomycin adenylylase, streptomycin adenylyltransferase, streptomycin-spectinomycin adenylyltransferase, AAD (3"), and aminoglycoside 3"-adenylyltransferase.

[edit] References

• IUBMB entry for 2.7.7.47
• BRENDA references for 2.7.7.47 (Recommended.)
• PubMed references for 2.7.7.47
• PubMed Central references for 2.7.7.47
• Google Scholar references for 2.7.7.47
• Harwood JH, Smith DH (1969). "Resistance factor-mediated streptomycin resistance". J. Bacteriol. 97: 1262–71. PMID 4887506. 

[edit] External links

The CAS registry number for this enzyme class is 52660-23-8.

• IUBMB entry for 2.7.7.47

• KEGG entry for 2.7.7.47

• BRENDA entry for 2.7.7.47

• NiceZyme view of 2.7.7.47

• EC2PDB: PDB structures for 2.7.7.47

• PRIAM entry for 2.7.7.47

• PUMA2 entry for 2.7.7.47

• IntEnz: Integrated Enzyme entry for 2.7.7.47

• MetaCyc entry for 2.7.7.47

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0009012: streptomycin 3-adenylyltransferase

• AMIGO entry for GO code 0009012: streptomycin 3-adenylyltransferase