Stratum lucidum

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Stratum lucidum
Section of epidermis. (Stratum lucidum labeled at left, second from top.)
Latin stratum lucidum epidermidis
Gray's subject #234 1064
Dorlands/Elsevier s_25/12761353
For the layer of the hippocampus, see stratum lucidum of hippocampus.

The stratum lucidum (Latin for "clear layer") is a thin, clear layer of dead skin cells in the epidermis, and is named for its translucent appearance under a microscope. It contains a clear substance called eleidin, which eventually becomes keratin. This layer is found beneath the stratum corneum of thick skin, and as such is only found on the palms of the hands and the soles of the feet. The keratinocytes of the stratum lucidum do not feature distinct boundaries and are filled with eleidin, an intermediate form of keratin.

The cells of the stratum lucidum are flattened and contain an oily substance that is the result of exocytosis of lamellar bodies accumulated while the keratinocytes are moving through the stratum spinosum and stratum granulosum. It is this substance that gives the stratum lucidum its waterproof properties, and, thus, it is also called the barrier layer of the skin.

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