STK25

From Wikipedia, the free encyclopedia

Serine/threonine kinase 25 (STE20 homolog, yeast)

Identifiers

STK25; DKFZp686J1430; SOK1; YSK1

External IDs

OMIM: 602255 MGI: 1891699 HomoloGene: 48428

Gene ontology
Molecular Function:	• nucleotide binding • magnesium ion binding • protein serine/threonine kinase activity • ATP binding • transferase activity • identical protein binding
Biological Process:	• protein amino acid phosphorylation • response to oxidative stress • signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006374 (mRNA)
NP_006365 (protein)

NM_021537 (mRNA)
NP_067512 (protein)

Location

Chr 2: 242.08 - 242.1 Mb

Chr 1: 95.45 - 95.47 Mb

Pubmed search

[1]

[2]

Serine/threonine kinase 25 (STE20 homolog, yeast), also known as STK25, is a human gene.^[1]

[edit] References

^ Entrez Gene: STK25 serine/threonine kinase 25 (STE20 homolog, yeast).

[edit] Further reading

Pombo CM, Bonventre JV, Molnar A, et al. (1997). "Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.". EMBO J. 15 (17): 4537–46. PMID 8887545.
Osada S, Izawa M, Saito R, et al. (1997). "YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways.". Oncogene 14 (17): 2047–57. doi:10.1038/sj.onc.1201043. PMID 9160885.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Preisinger C, Short B, De Corte V, et al. (2004). "YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.". J. Cell Biol. 164 (7): 1009–20. doi:10.1083/jcb.200310061. PMID 15037601.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Findlay GM, Yan L, Procter J, et al. (2007). "A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.". Biochem. J. 403 (1): 13–20. doi:10.1042/BJ20061881. PMID 17253963.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.