STK16

From Wikipedia, the free encyclopedia

Serine/threonine kinase 16

PDB rendering based on 2buj.

Available structures: 2buj

Identifiers

Symbol(s)

STK16; FLJ39635; KRCT; MPSK; PKL12; TSF1

External IDs

OMIM: 604719 MGI: 1313271 HomoloGene: 2739

Gene ontology
Molecular Function:	• nucleotide binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• membrane
Biological Process:	• protein complex assembly • protein amino acid phosphorylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001008910 (mRNA)
NP_001008910 (protein)

NM_011494 (mRNA)
NP_035624 (protein)

Location

Chr 2: 219.82 - 219.82 Mb

Chr 1: 75.09 - 75.1 Mb

Pubmed search

[1]

[2]

Serine/threonine kinase 16, also known as STK16, is a human gene.^[1]

[edit] References

^ Entrez Gene: STK16 serine/threonine kinase 16.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Ligos JM, Gerwin N, Fernández P, et al. (1998). "Cloning, expression analysis, and functional characterization of PKL12, a member of a new subfamily of ser/thr kinases.". Biochem. Biophys. Res. Commun. 249 (2): 380–4. doi:10.1006/bbrc.1998.9163. PMID 9712705.
Berson AE, Young C, Morrison SL, et al. (1999). "Identification and characterization of a myristylated and palmitylated serine/threonine protein kinase.". Biochem. Biophys. Res. Commun. 259 (3): 533–8. doi:10.1006/bbrc.1999.0811. PMID 10364453.
Ohta S, Takeuchi M, Deguchi M, et al. (2001). "A novel transcriptional factor with Ser/Thr kinase activity involved in the transforming growth factor (TGF)-beta signalling pathway.". Biochem. J. 350 Pt 2: 395–404. PMID 10947953.
Ligos JM, de Lera TL, Hinderlich S, et al. (2002). "Functional interaction between the Ser/Thr kinase PKL12 and N-acetylglucosamine kinase, a prominent enzyme implicated in the salvage pathway for GlcNAc recycling.". J. Biol. Chem. 277 (8): 6333–43. doi:10.1074/jbc.M105766200. PMID 11741987.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Guinea B, Ligos JM, Laín de Lera T, et al. (2006). "Nucleocytoplasmic shuttling of STK16 (PKL12), a Golgi-resident serine/threonine kinase involved in VEGF expression regulation.". Exp. Cell Res. 312 (2): 135–44. doi:10.1016/j.yexcr.2005.10.010. PMID 16310770.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.