Steroid N-acetylglucosaminyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a steroid N-acetylglucosaminyltransferase (EC 2.4.1.39) is an enzyme that catalyzes the chemical reaction

UDP-N-acetyl-D-glucosamine + estradiol-17alpha 3-D-glucuronoside UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside

Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and estradiol-17alpha 3-D-glucuronoside, whereas its two products are UDP and 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase. Other names in common use include hydroxy steroid acetylglucosaminyltransferase, steroid acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-steroid, and acetylglucosaminyltransferase.

[edit] References

• IUBMB entry for 2.4.1.39
• BRENDA references for 2.4.1.39 (Recommended.)
• PubMed references for 2.4.1.39
• PubMed Central references for 2.4.1.39
• Google Scholar references for 2.4.1.39
• Collins DC, Jirku H, Layne DS (1968). "Steroid N-acetylglucosaminyl transferase. Localization and some properties of the enzyme in rabbit tissues". J. Biol. Chem. 243: 2928–33. PMID 5660254. 

[edit] External links

The CAS registry number for this enzyme class is 9033-56-1.

• IUBMB entry for 2.4.1.39

• KEGG entry for 2.4.1.39

• BRENDA entry for 2.4.1.39

• NiceZyme view of 2.4.1.39

• EC2PDB: PDB structures for 2.4.1.39

• PRIAM entry for 2.4.1.39

• PUMA2 entry for 2.4.1.39

• IntEnz: Integrated Enzyme entry for 2.4.1.39

• MetaCyc entry for 2.4.1.39

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047261: steroid N-acetylglucosaminyltransferase

• AMIGO entry for GO code 0047261: steroid N-acetylglucosaminyltransferase