Stauffer syndrome

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Stauffer syndrome
Classification and external resources
DiseasesDB 29132

Stauffer syndrome is a constellation of signs and symptoms of liver dysfunction that arise due to presence of renal cell carcinoma[1] but are not due to tumour inflitration into the liver and/or intrinsic liver disease; it is a paraneoplastic syndrome.[2]

It leads to elevated liver function tests, which results from cholestatis, i.e. a sessation of bile flow. The symptoms resolve if the renal cell cancer is successfully treated.[2]

[edit] Eponym

It was first characterized in 1961.[3][4]

[edit] References

  1. ^ Stedman's Medical Dictionary. URL: http://www.emedicine.com/asp/dictionary.asp?keyword=Stauffer+syndrome. Accessed on: April 14, 2007.
  2. ^ a b Jakse G, Madersbacher H (1978). "[Stauffer's syndrome. Reversible hepatic dysfunction in renal cell carcinoma (author's transl)]". Wien Klin Wochenschr 90 (8): 268–70. PMID 636440. 
  3. ^ Stauffer MH. Nephrogenic hepatomegaly. Gastroenterology. 1961;40:694.
  4. ^ Stauffer's Syndrome Variant with Cholestatic Jaundice A Case Report. Retrieved on 2007-12-29.

[edit] External links

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