ST6GALNAC1
From Wikipedia, the free encyclopedia
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
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Identifiers | ||||||||||||||
Symbol(s) | ST6GALNAC1; HSY11339; SIAT7A; ST6GalNAcI | |||||||||||||
External IDs | OMIM: 610138 MGI: 1341826 HomoloGene: 7937 | |||||||||||||
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RNA expression pattern | ||||||||||||||
Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 55808 | 20445 | ||||||||||||
Ensembl | ENSG00000070526 | n/a | ||||||||||||
Uniprot | Q9NSC7 | n/a | ||||||||||||
Refseq | NM_018414 (mRNA) NP_060884 (protein) |
XM_001005669 (mRNA) XP_001005669 (protein) |
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Location | Chr 17: 72.13 - 72.15 Mb | n/a | ||||||||||||
Pubmed search | [1] | [2] |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, also known as ST6GALNAC1, is a human gene.[1]
[edit] References
[edit] Further reading
- Lee YC, Kaufmann M, Kitazume-Kawaguchi S, et al. (1999). "Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV.". J. Biol. Chem. 274 (17): 11958-67. PMID 10207017.
- Ikehara Y, Kojima N, Kurosawa N, et al. (2000). "Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens.". Glycobiology 9 (11): 1213-24. PMID 10536037.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi: . PMID 12477932.
- Donadio S, Dubois C, Fichant G, et al. (2004). "Recognition of cell surface acceptors by two human alpha-2,6-sialyltransferases produced in CHO cells.". Biochimie 85 (3-4): 311-21. PMID 12770770.
- Julien S, Krzewinski-Recchi MA, Harduin-Lepers A, et al. (2003). "Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA.". Glycoconj. J. 18 (11-12): 883-93. PMID 12820722.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi: . PMID 12975309.
- Sewell R, Bäckström M, Dalziel M, et al. (2006). "The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.". J. Biol. Chem. 281 (6): 3586-94. doi: . PMID 16319059.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi: . PMID 16344560.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi: . PMID 17081983.