SRGAP3

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SLIT-ROBO Rho GTPase activating protein 3
PDB rendering based on 2gnc.
Available structures: 2gnc
Identifiers
Symbol(s) SRGAP3; ARHGAP14; KIAA0411; MEGAP; SRGAP2; WRP
External IDs OMIM: 606525 MGI: 2152938 HomoloGene: 56686
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9901 259302
Ensembl ENSG00000196220 ENSMUSG00000030257
Uniprot O43295 Q91Z68
Refseq NM_001033116 (mRNA)
NP_001028288 (protein)		 NM_153070 (mRNA)
NP_694710 (protein)
Location Chr 3: 9 - 9.27 Mb Chr 6: 112.68 - 112.91 Mb
Pubmed search [1] [2]

SLIT-ROBO Rho GTPase activating protein 3, also known as SRGAP3, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: SRGAP3 SLIT-ROBO Rho GTPase activating protein 3.

[edit] Further reading

  • Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954. 
  • Ishikawa K, Nagase T, Nakajima D, et al. (1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 4 (5): 307-13. PMID 9455477. 
  • Hirosawa M, Nagase T, Ishikawa K, et al. (2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.". DNA Res. 6 (5): 329-36. PMID 10574461. 
  • Wong K, Ren XR, Huang YZ, et al. (2001). "Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.". Cell 107 (2): 209-21. PMID 11672528. 
  • Endris V, Wogatzky B, Leimer U, et al. (2002). "The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation.". Proc. Natl. Acad. Sci. U.S.A. 99 (18): 11754-9. doi:10.1073/pnas.162241099. PMID 12195014. 
  • Olave I, Wang W, Xue Y, et al. (2002). "Identification of a polymorphic, neuron-specific chromatin remodeling complex.". Genes Dev. 16 (19): 2509-17. doi:10.1101/gad.992102. PMID 12368262. 
  • Soderling SH, Binns KL, Wayman GA, et al. (2003). "The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling.". Nat. Cell Biol. 4 (12): 970-5. doi:10.1038/ncb886. PMID 12447388. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Katoh M, Katoh M (2004). "FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.". Int. J. Mol. Med. 11 (6): 791-7. PMID 12736724. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Yang Y, Marcello M, Endris V, et al. (2006). "MEGAP impedes cell migration via regulating actin and microtubule dynamics and focal complex formation.". Exp. Cell Res. 312 (12): 2379-93. doi:10.1016/j.yexcr.2006.04.001. PMID 16730001. 
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