SraH RNA

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SraH RNA
Template:Abbreviation
Type: Gene; sRNA;
2° structure: Predicted; PFOLD
Seed alignment: Bateman A
Avg length: 108.4 nucleotides
Avg identity: 79%

SraH is a is a small non-coding RNA (ncRNA). It is the functional product of a gene which is not translated into protein.

This non-coding RNA was discovered in the bacteria Escherichia coli during a large scale computational screen for transcription signals and genomic features of known small RNA-encoding genes[1]. During this screen 14 novel ncRNA genes were identified.

The expression of SraH was experimentally confirmed by Northern blotting[1]. Its expression is highly abundant in stationary growth phase but low levels of expression can still be detected in exponentially growing cells [1]. The function of SraH is not known but it is likely to act as an antisense regulator of some bacterial genes.

[edit] References

  1. ^ a b c Argaman L, Hershberg R, Vogel J, et al (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli". Curr. Biol. 11 (12): 941–50. PMID 11448770. 

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