Talk:Spironolactone

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As far as I know, spironolactone also has anti-androgenic affect as an adverse effect. can anyone vertify this for me?

There is absolutely no need to doubt this. Spironolactone is a commonly perscribed anti-androgen for transexual MTFs. It's one of the safest anti-androgens to use, and antagonizes both the production of androgens and their ability to react with the body. The adverse effects listed "gynecomastia", "testicular atrophy", and "impotence" are all results of the anti-androgen effects of spironolactone. As it is an anti-androgen, I would also presume that it also reversibly decreases fertility. --Puellanivis 19:50, 2 October 2006 (UTC)

True. Trust me.

This page needs info about the (new?) topical spironolactone used for hairloss in men (note: not an oral pill but lotion applied directly on the scalp to avoid side effects in men)

• I'll add it later today ... - Alison ☺ 01:18, 2 May 2007 (UTC)

What are the methods of taking Spironolactone? I would more specifically like to know if it could be taken into the blood better through sublingual absorption after rinsing the mouth with a strong liquid like Listerine, or while doing cardiovascular exercise. Is it soluable with alcohol? Email me @ clandestinevillian@yahoo.com —Preceding unsigned comment added by 64.203.251.204 (talk) 15:07, 14 October 2007 (UTC)

While I take Estradiol sublingually, I still swallow my Spironolactone tablets. I have heard that it's probably not a good idea to take Spiro sublingually. Most people find the taste very unpleasant and taking it sublingually could result in systemic toxicity. Andrea Parton (talk) 10:12, 12 April 2008 (UTC)