Sphingosine beta-galactosyltransferase

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In enzymology, a sphingosine beta-galactosyltransferase (EC 2.4.1.23) is an enzyme that catalyzes the chemical reaction

UDP-galactose + sphingosine UDP + psychosine

Thus, the two substrates of this enzyme are UDP-galactose and sphingosine, whereas its two products are UDP and psychosine.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:sphingosine 1-beta-galactosyltransferase. Other names in common use include psychosine-UDP galactosyltransferase, galactosyl-sphingosine transferase, psychosine-uridine diphosphate galactosyltransferase, UDP-galactose:sphingosine O-galactosyl transferase, uridine diphosphogalactose-sphingosine beta-galactosyltransferase, and UDP-galactose:sphingosine 1-beta-galactotransferase. This enzyme participates in sphingolipid metabolism.

[edit] References

• IUBMB entry for 2.4.1.23
• BRENDA references for 2.4.1.23 (Recommended.)
• PubMed references for 2.4.1.23
• PubMed Central references for 2.4.1.23
• Google Scholar references for 2.4.1.23
• CLELAND WW, KENNEDY EP (1960). "The enzymatic synthesis of psychosine". J. Biol. Chem. 235: 45–51. PMID 13810623. 

[edit] External links

The CAS registry number for this enzyme class is 9032-90-0.

• IUBMB entry for 2.4.1.23

• KEGG entry for 2.4.1.23

• BRENDA entry for 2.4.1.23

• NiceZyme view of 2.4.1.23

• EC2PDB: PDB structures for 2.4.1.23

• PRIAM entry for 2.4.1.23

• PUMA2 entry for 2.4.1.23

• IntEnz: Integrated Enzyme entry for 2.4.1.23

• MetaCyc entry for 2.4.1.23

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047258: sphingosine beta-galactosyltransferase

• AMIGO entry for GO code 0047258: sphingosine beta-galactosyltransferase