Spectrin repeat

From Wikipedia, the free encyclopedia

Spectrin repeat
Identifiers
Symbol Spectrin
Pfam PF00435
InterPro IPR002017
PROSITE PDOC50083
SCOP 1aj3
OPM family 79
OPM protein 2spc
Available PDB structures:

1s35A:1063-1166 1sjjB:395-500 1quuA:401-506 1hciB:401-506 2spcB:1393-1497 1u5pA:1663-1767 1u4qA:1663-1767 1owaA:53-156 1cunC:1875-1979 1aj3 :1772-1869 1wlxA:528-639

Spectrin repeats[1] are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The spectrin repeat forms a three-helix bundle.

[edit] Human proteins containing this domain

ACTN1; ACTN2; ACTN3; ACTN4; AKAP6; C14orf49; CATX-15; DMD; DRP2; DST; KALRN; MACF1; MCF2L; SPNB4; SPTA1; SPTAN1; SPTB; SPTBN1; SPTBN2; SPTBN3; SPTBN4; SPTBN5; SYNE1; SYNE2; TRIO; UTRN;

[edit] References

  1. ^ Harrison SC, Yan Y, Winograd E, Viel A, Cronin T, Branton D (1993). "Crystal structure of the repetitive segments of spectrin". Science 262 (5142): 2027–2030. doi:10.1126/science.8266097. PMID 8266097. 
 This membrane protein-related article is a stub. You can help Wikipedia by expanding it.