Sodium salicylate
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| Sodium salicylate | |
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| IUPAC name | Sodium salicylate |
| Other names | Salsonin, Monosodium salicylate, Sodium o-hydroxybenzoate, Sodium 2-hydroxybenzoate, Salicylic acid sodium salt, Monosodium 2-hydroxybenzoate, Diuratin, ... |
| Identifiers | |
| CAS number | [54-21-7] |
| PubChem | |
| EINECS number | |
| KEGG | |
| RTECS number | VO5075000 |
| SMILES | [Na+].O=C([O-])c1ccccc1O |
| InChI | 1/C7H6O3.Na/c8-6-4-2-1- 3-5(6)7(9)10;/h1-4,8H,(H,9,10); /q;+1/p-1/fC7H5O3.Na/q-1;m |
| Properties | |
| Molecular formula | C7H5NaO3 |
| Molar mass | 160.11 g/mol |
| Appearance | White crystals |
| Melting point |
200 °C |
| Solubility in water | ~ 1000 g/l at 20 °C |
| Hazards | |
| Main hazards | Harmful |
| NFPA 704 |
 1
1
0
|
| R-phrases | R22, R36/37/38 |
| S-phrases | S24/25, S26, S36/37/39 |
| Autoignition temperature |
> 250 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure.
It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells [1][2][3] and also necrosis [4]. It is also a potential replacement for aspirin for people sensitive to it.
[edit] External links
- Chemicalland21
- Some synonyms
- Safety data for sodium salicylate at Oxford University
- Sodium salicylate, definitions at National Cancer Institute
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