SNF1LK

From Wikipedia, the free encyclopedia

SNF1-like kinase

Identifiers

SNF1LK; MSK; SIK

External IDs

OMIM: 605705 MGI: 104754 HomoloGene: 7847

Gene ontology
Molecular Function:	• nucleotide binding • magnesium ion binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• cytoplasm
Biological Process:	• protein amino acid phosphorylation • cell cycle • protein kinase cascade • multicellular organismal development • regulation of progression through mitotic cell cycle • regulation of cell differentiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_173354 (mRNA)
NP_775490 (protein)

NM_010831 (mRNA)
NP_034961 (protein)

Location

Chr 21: 43.66 - 43.67 Mb

Chr 17: 31.57 - 31.58 Mb

Pubmed search

[1]

[2]

SNF1-like kinase, also known as SNF1LK, is a human gene.^[1]

[edit] References

^ Entrez Gene: SNF1LK SNF1-like kinase.

[edit] Further reading

Takemori H, Kajimura J, Okamoto M (2007). "TORC-SIK cascade regulates CREB activity through the basic leucine zipper domain.". FEBS J. 274 (13): 3202-9. doi:10.1111/j.1742-4658.2007.05889.x. PMID 17565599.
Al-Hakim AK, Göransson O, Deak M, et al. (2006). "14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.". J. Cell. Sci. 118 (Pt 23): 5661-73. doi:10.1242/jcs.02670. PMID 16306228.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Lizcano JM, Göransson O, Toth R, et al. (2005). "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.". EMBO J. 23 (4): 833-43. doi:10.1038/sj.emboj.7600110. PMID 14976552.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311-9. doi:10.1038/35012518. PMID 10830953.
Nishimura Y, Hayashi M, Inada H, Tanaka T (1999). "Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.". Biochem. Biophys. Res. Commun. 254 (1): 21-6. doi:10.1006/bbrc.1998.9876. PMID 9920726.
Ruiz JC, Conlon FL, Robertson EJ (1995). "Identification of novel protein kinases expressed in the myocardium of the developing mouse heart.". Mech. Dev. 48 (3): 153-64. PMID 7893599.