SNF1LK2

From Wikipedia, the free encyclopedia

SNF1-like kinase 2

Identifiers

SNF1LK2; DKFZp434K1115; KIAA0781; LOH11CR1I; QIK; SIK2

External IDs

OMIM: 608973 MGI: 2445031 HomoloGene: 22875

Gene ontology
Molecular Function:	• nucleotide binding • magnesium ion binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• nucleus • cytoplasm
Biological Process:	• protein amino acid phosphorylation • protein kinase cascade • regulation of insulin receptor signaling pathway

Orthologs

Human

Mouse

Refseq

NM_015191 (mRNA)
NP_056006 (protein)

NM_178710 (mRNA)
NP_848825 (protein)

Location

Chr 11: 110.98 - 111.1 Mb

Chr 9: 50.65 - 50.76 Mb

Pubmed search

[1]

[2]

SNF1-like kinase 2, also known as SNF1LK2, is a human gene.^[1]

[edit] References

^ Entrez Gene: SNF1LK2 SNF1-like kinase 2.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (5): 277-86. PMID 9872452.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Horike N, Takemori H, Katoh Y, et al. (2003). "Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2.". J. Biol. Chem. 278 (20): 18440-7. doi:10.1074/jbc.M211770200. PMID 12624099.
Katoh M, Katoh M (2004). "Identification and characterization of human KIAA1391 and mouse Kiaa1391 genes encoding novel RhoGAP family proteins with RA domain and ANXL repeats.". Int. J. Oncol. 23 (5): 1471-6. PMID 14532992.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Lizcano JM, Göransson O, Toth R, et al. (2005). "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.". EMBO J. 23 (4): 833-43. doi:10.1038/sj.emboj.7600110. PMID 14976552.
Katoh M, Katoh M (2004). "Identification and characterization of human FOXN5 and rat Foxn5 genes in silico.". Int. J. Oncol. 24 (5): 1339-44. PMID 15067358.
Screaton RA, Conkright MD, Katoh Y, et al. (2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.". Cell 119 (1): 61-74. doi:10.1016/j.cell.2004.09.015. PMID 15454081.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Katoh Y, Takemori H, Min L, et al. (2004). "Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm.". Eur. J. Biochem. 271 (21): 4307-19. doi:10.1111/j.1432-1033.2004.04372.x. PMID 15511237.