From Wikipedia, the free encyclopedia
| Small nucleolar RNA Z242 |
 |
| Type: |
Gene; snRNA; guide; CD-box; |
| 2° structure: |
Predicted; PFOLD; Moxon SJ |
| Seed alignment: |
Moxon SJ |
| Avg length: |
191.1 nucleotides |
| Avg identity: |
82% |
|
Small nucleolar RNA Z242 is a non-coding RNA (ncRNA) molecule which function in the biogenesis of other small nuclear RNAs (snRNAs). This small nucleolar RNA (snoRNA) is a modifiying RNA and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
snoRNA Z242 was identified in rice Oryza sativa [1]and is predicted to belong to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs[2].
[edit] References
- ^ Chen CL, Liang D, Zhou H, Zhuo M, Chen YQ, Qu LH (2003). "The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa". Nucleic Acids Res. 31 (10): 2601–13. PMID 12736310.
- ^ Galardi, S; Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I (2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Mol Cell Biol 22: 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMID 12215523.
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