Small nucleolar RNA SNORD78

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Small nucleolar RNA SNORD78
Template:Abbreviation
Type: Gene; snRNA; guide; CD-box;
2° structure: Predicted; RNAalifold
Seed alignment: Marantidis E.
Avg length: 65.8 nucleotides
Avg identity: 90%

U78 belongs to the CD family of snoRNAs. It is predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit at position G4593.[1] The snoRNAs U44, U47, U74, U75, U76, U77, U79, U80 and U81, also of the C/D family, share the same host gene with U78 (protein non-coding).[2]

[edit] References

  1. ^ Tycowski, KT; Aab A, Steitz JA (2004). "Guide RNAs with 5' caps and novel box C/D snoRNA-like domains for modification of snRNAs in metazoa". Curr Biol. 14: 1985–1995. doi:10.1016/j.cub.2004.11.003. PMID 15556860. 
  2. ^ Lestrade, L; Weber MJ (2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Res. 34: D158–D162. doi:10.1093/nar/gkj002. PMID 16381836. 

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