Small nucleolar RNA SNORD27

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Small nucleolar RNA SNORD27
Template:Abbreviation
Type: Gene; snRNA; guide; CD-box;
2° structure: Predicted; Moxon SJ, Daub J
Seed alignment: Griffiths-Jones SR, Moxon SJ, Daub J
Avg length: 77.9 nucleotides
Avg identity: 68%

Small nucleolar RNA SNORD27 (U27) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U27 is encoded within the U22 snoRNA host gene (UHG) in mammals[1] and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.[2] This family also contains several related snoRNAs from yeast and plants.

[edit] References

  1. ^ Tycowski, KT; Shu MD, Steitz JA (1996). "A mammalian gene with introns instead of exons generating stable RNA products". Nature 379: 464–466. doi:10.1038/379464a0. PMID 8559254. 
  2. ^ Tycowski, KT; Smith CM, Shu MD, Steitz JA (1996). "A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus". Proc Natl Acad Sci U S A 93: 14480–14485. doi:10.1073/pnas.93.25.14480. PMID 8962077. 

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