From Wikipedia, the free encyclopedia
Small nucleolar RNA SNORD21 |
|
Type: |
Gene; snRNA; guide; CD-box; |
2° structure: |
Predicted; PFOLD; Griffiths-Jones SR, Daub J |
Seed alignment: |
Griffiths-Jones SR |
Avg length: |
89.1 nucleotides |
Avg identity: |
66% |
|
U21 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U21 is encoded within an intron of the gene for ribosomal protein L5 in mammals [1], but within introns of the ADP ribosylation factor gene in Drosophila [2]. U21 snoRNA has a 13 nucleotide region of complementarity with an invariant region of eukaryotic 28S ribosomal RNA.
[edit] References
- [1] Qu, LH; Nicoloso M, Michot B, Azum MC, Caizergues-Ferrer M, Renalier MH, Bachellerie JP (1994). "U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals". Nucleic Acids Res 22: 4073–4081. doi:10.1093/nar/22.20.4073. PMID 7937132.
- [2] Renalier, MH; Nicoloso M, Qu LH, Bachellerie JP (1996). "SnoRNA U21 is also intron-encoded in Drosophila melanogaster but in a different host-gene as compared to warm-blooded vertebrates". FEBS Lett 379: 212–216. doi:10.1016/0014-5793(95)01511-6. PMID 8603691.
[edit] External links