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| Small nucleolar RNA SNORA71 |
 |
| Type: |
Gene; snRNA; guide; HACA-box; |
| 2° structure: |
Predicted; PFOLD |
| Seed alignment: |
Griffiths-Jones SR |
| Avg length: |
128.6 nucleotides |
| Avg identity: |
71% |
|
In molecular biology, U71 belongs to the H/ACA class of Small nucleolar RNA (snoRNAs). snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs.[1] Targets may include ribosomal and spliceosomal RNAs but the exact function of many snoRNAs, including U71, is unclear.
[edit] References
- Ganot, P; Caizergues-Ferrer M, Kiss T (1997). "The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation". Genes Dev 11: 941–956. doi:10.1101/gad.11.7.941. PMID 9106664.
- Bachellerie, JP; Cavaille J, Huttenhofer A (2002). "The expanding snoRNA world". Biochimie 84: 775–790. doi:10.1016/S0300-9084(02)01402-5. PMID 12457565.
[edit] External links
