Small nucleolar RNA SNORA67

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Small nucleolar RNA SNORA67
Template:Abbreviation
Type: Gene; snRNA; guide; HACA-box;
2° structure: Predicted; RNAalifold; Daub J
Seed alignment: Moxon SJ
Avg length: 139.9 nucleotides
Avg identity: 73%

snoRNA U67 is a non-coding RNA molecule that belongs to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines.[1] This snoRNA guides pseudouridylation of position U1445 in 18S rRNA[2]. This RNA is expressed from the intron of the host gene EIF4A1.

[edit] References

  1. ^ Kiss, T (2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell 109: 145–148. doi:10.1016/S0092-8674(02)00718-3. PMID 12007400. 
  2. ^ Ganot P, Bortolin ML, Kiss T (1997). "Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs". Cell 89 (5): 799–809. PMID 9182768. 

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