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| Small nucleolar RNA SNORA17 |
 |
| Type: |
Gene; snRNA; guide; HACA-box; |
| 2° structure: |
Predicted; RNAalifold |
| Seed alignment: |
Marantidis E |
| Avg length: |
131.5 nucleotides |
| Avg identity: |
79% |
|
In molecular biology, SNORA17 (also known as ACA17) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.[1] Specifically, it is predicted to guide pseudouridylation of the 28S rRNA at positions U4659 and U4598. It shares the same host gene together with ACA43.
Interestingly, there are many closely related sequences that do not appear to have conserved H and ACA boxes, and may be pseudogenes.
[edit] References
- Ofengand, J; Bakin A (1997). "Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts". J Mol Biol. 266: 246–268. doi:10.1006/jmbi.1996.0737. PMID 9047361.
[edit] External links
