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| Small Cajal body specific RNA 4 |
 |
| Type: |
Gene; snRNA; guide; scaRNA; |
| 2° structure: |
Predicted; RNAFOLD; Moxon SJ |
| Seed alignment: |
Moxon SJ |
| Avg length: |
127.2 nucleotides |
| Avg identity: |
88% |
|
In molecular biology, small Cajal body specific RNA 4 (also known as ACA26) is believed to be a guide RNA of the H/ACA box class, since it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs, and is found associated with GAR1.[1] In particular, ACA26 is predicted to guide the pseudouridylation of residues U39 and U41 in U2 snRNA.[1] Such scaRNAs are a specific class of small nuclear RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.[2]
[edit] References
- Lestrade, L; Weber MJ (2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Res. 34: D158–D162. doi:10.1093/nar/gkj002. PMID 16381836.
[edit] External links
