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| Small Cajal body specific RNA 25 |
 |
| Type: |
Gene; snRNA; guide; scaRNA; |
| 2° structure: |
Predicted; RNAalifold |
| Seed alignment: |
Marantidis E |
| Avg length: |
134.6 nucleotides |
| Avg identity: |
80% |
|
Small Cajal body specific RNA 25 (otherwise known as scaRNA25, HBI-100, MBI-100 and MBI-114) is a scaRNA which are a class of ncRNAs characterised as a small nuclear RNAs localised to the Cajal bodies [1]. ScaRNA25 was originally identified in a large scale cloning project in mouse [2]. Later sequence analysis predicted that this RNA guides the pseudouridylation of position U40 in the U6 snRNA [2].
[edit] References
- ^ Darzacq, X; Jady BE, Verheggen C, Kiss AM, Bertrand E, Kiss T (2002). "Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs". EMBO J. 21: 2746–2756. doi:10.1093/emboj/21.11.2746. PMID 12032087.
- ^ a b Huttenhofer, A; Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J (2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". EMBO J. 20: 2943–2953. doi:10.1093/emboj/20.11.2943. PMID 11387227.
[edit] External links
