SLITRK6

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SLIT and NTRK-like family, member 6
Identifiers
Symbol(s) SLITRK6; MGC119595; MGC119596; MGC119597
External IDs OMIM: 609681 MGI: 2443198 HomoloGene: 12986
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 84189 239250
Ensembl ENSG00000184564 ENSMUSG00000045871
Uniprot Q9H5Y7 Q8C110
Refseq NM_032229 (mRNA)
NP_115605 (protein)		 NM_175499 (mRNA)
NP_780708 (protein)
Location Chr 13: 85.27 - 85.27 Mb Chr 14: 109.63 - 109.64 Mb
Pubmed search [1] [2]

SLIT and NTRK-like family, member 6, also known as SLITRK6, is a human gene.[1]

Members of the SLITRK family, such as SLITRK6, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK6, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: SLITRK6 SLIT and NTRK-like family, member 6.

[edit] Further reading

  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Aruga J, Yokota N, Mikoshiba K (2004). "Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.". Gene 315: 87–94. PMID 14557068. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336. 
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901. 
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