SLC6A5

From Wikipedia, the free encyclopedia


Solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Identifiers
Symbol(s) SLC6A5; GLYT2; NET1
External IDs OMIM: 604159 MGI: 105090 HomoloGene: 37901
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9152 104245
Ensembl ENSG00000165970 n/a
Uniprot Q9Y345 n/a
Refseq NM_004211 (mRNA)
NP_004202 (protein)		 NM_148931 (mRNA)
NP_683733 (protein)
Location Chr 11: 20.58 - 20.63 Mb n/a
Pubmed search [1] [2]

Solute carrier family 6 (neurotransmitter transporter, glycine), member 5, also known as SLC6A5, is a human gene.[1]


[edit] See also

[edit] References

  1. ^ Entrez Gene: SLC6A5 solute carrier family 6 (neurotransmitter transporter, glycine), member 5.

[edit] Further reading

  • López-Corcuera B, Aragón C, Geerlings A (2002). "Regulation of glycine transporters.". Biochem. Soc. Trans. 29 (Pt 6): 742–5. PMID 11709067. 
  • Morrow JA, Collie IT, Dunbar DR, et al. (1998). "Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome.". FEBS Lett. 439 (3): 334–40. PMID 9845349. 
  • Gallagher MJ, Burgess LH, Brunden KR (1999). "Characterization of multiple forms of the human glycine transporter type-2.". Brain Res. Mol. Brain Res. 70 (1): 101–15. PMID 10381548. 
  • Evans J, Herdon H, Cairns W, et al. (2000). "Cloning, functional characterisation and population analysis of a variant form of the human glycine type 2 transporter.". FEBS Lett. 463 (3): 301–6. PMID 10606742. 
  • Martínez-Maza R, Poyatos I, López-Corcuera B, et al. (2001). "The role of N-glycosylation in transport to the plasma membrane and sorting of the neuronal glycine transporter GLYT2.". J. Biol. Chem. 276 (3): 2168–73. doi:10.1074/jbc.M006774200. PMID 11036075. 
  • Geerlings A, Núñez E, Rodenstein L, et al. (2002). "Glycine transporter isoforms show differential subcellular localization in PC12 cells.". J. Neurochem. 82 (1): 58–65. PMID 12091465. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Mahendrasingam S, Wallam CA, Hackney CM (2003). "Two approaches to double post-embedding immunogold labeling of freeze-substituted tissue embedded in low temperature Lowicryl HM20 resin.". Brain Res. Brain Res. Protoc. 11 (2): 134–41. PMID 12738009. 
  • Baliova M, Betz H, Jursky F (2004). "Calpain-mediated proteolytic cleavage of the neuronal glycine transporter, GlyT2.". J. Neurochem. 88 (1): 227–32. PMID 14675166. 
  • Tsutsumi S, Kamata N, Vokes TJ, et al. (2004). "The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD).". Am. J. Hum. Genet. 74 (6): 1255–61. doi:10.1086/421527. PMID 15124103. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Jamra RA, Villela AW, Klein K, et al. (2006). "No association between genetic variants at the GLYT2 gene and bipolar affective disorder and schizophrenia.". Psychiatr. Genet. 16 (3): 91. doi:10.1097/01.ypg.0000199450.07786.ab. PMID 16691125. 
  • Rees MI, Harvey K, Pearce BR, et al. (2006). "Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease.". Nat. Genet. 38 (7): 801–6. doi:10.1038/ng1814. PMID 16751771. 
  • Eulenburg V, Becker K, Gomeza J, et al. (2006). "Mutations within the human GLYT2 (SLC6A5) gene associated with hyperekplexia.". Biochem. Biophys. Res. Commun. 348 (2): 400–5. doi:10.1016/j.bbrc.2006.07.080. PMID 16884688. 
 This membrane protein-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Membrane proteins, carrier proteins: membrane transport proteins
ABC-transporter
A1, A2, A3, A4, A7, A8, A12, B1

B2-3, B2, B3, B4, B5, B6, B7, B9, B11

C1, C2, C3, C4, C5, C6, C8, C8-9, C10, C13, C11

D1, D2, D3, D4, E1, F1, F2

G1, G2, G4, Sterolin (G5, G8)
Solute carrier
1A1-7, 1A1, 1A2, 1A3, 1A4, 1A5, 2A1, 2A2, 2A3, 2A4, 2A5, 2A6, 2A8, 2A9, 2A10, 2A12, 3A1, 3A2, 4A1, 4A2, 4A3, 4A4, 4A5, 4A7, 4A8, 4A11, 5A1-2, 5A1, 5A3, 5A5, 5A8, 6A1, 6A2, 6A3, 6A4, 6A5, 6A8, 6A9, 6A19, 7A1, 7A2, 7A3, 7A4, 7A5, 7A7, 7A8, 7A9, 7A11, 8A1-3, 9A1, 9A2, 9A3, 9A3R1, 9A3R2, 9A5, 9A6, 9A8, 10A1, 10A2, 10A3, 10A7, 11A1, 11A2, 11A3, 12A1-2, 12A3, 12A4, 12A5, 12A6, 12A7, 14A1, 13A3, 14A2, 15A1, 15A2, 16A1, 16A2, 16A3, 16A4, 17A1, 17A5, 17A6-8, 17A7, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 20A1, 20A2, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 22A7, 22A9, 22A11, 22A12, 22A18, 23A1, 23A2, 24A1-2, 24A5, 25A1, 25A3, 25A4, 25A4-6, 25A8, 25A10, 25A11, 25A12, 25A13, 25A14, 25A15, 25A17, 25A19, 25A20, 25A27, 25A31, 25A37, 25A39, 26A2, 26A3, 26A4, 26A5, 26A6, 26A7, 26A8, 27A1, 27A2, 27A3, 27A4, 28A1, 28A2, 29A1, 29A2, 29A4, 30A4, 30A7, 30A8, 31A1, 31A2, 32A1, 34A1, 34A2, 34A3, 35A1, 35A2, 35B2, 35B4, 35C1, 36A1, 37A4, 38A2, 38A3, 39A1, 39A2, 39A3, 39A4, 39A6, 39A7, 40A1, 43A1 44A1, 44A2, 44A4, 45A2, O1A2, O1B1, O1B3, O2B1, O431, O4A1
Monosaccharide
Other