SLC27A6

From Wikipedia, the free encyclopedia

Solute carrier family 27 (fatty acid transporter), member 6

Identifiers

SLC27A6; ACSVL2; DKFZp779M0564; FACVL2; FATP6; VLCS-H1

External IDs

OMIM: 604196 MGI: 3036230 HomoloGene: 38385

Gene ontology
Molecular Function:	• nucleotide binding • long-chain-fatty-acid-CoA ligase activity • ligase activity
Cellular Component:	• membrane • integral to membrane
Biological Process:	• very-long-chain fatty acid metabolic process • lipid metabolic process • lipid transport • metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_001017372 (mRNA)
NP_001017372 (protein)

XM_128932 (mRNA)
XP_128932 (protein)

Location

Chr 5: 128.33 - 128.4 Mb

Chr 18: 58.68 - 58.74 Mb

Pubmed search

[1]

[2]

Solute carrier family 27 (fatty acid transporter), member 6, also known as SLC27A6, is a human gene.^[1]

This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene.^[1]

[edit] References

^ ^a ^b Entrez Gene: SLC27A6 solute carrier family 27 (fatty acid transporter), member 6.

[edit] Further reading

Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Gimeno RE, Ortegon AM, Patel S, et al. (2003). "Characterization of a heart-specific fatty acid transport protein.". J. Biol. Chem. 278 (18): 16039–44. doi:10.1074/jbc.M211412200. PMID 12556534.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Steinberg SJ, Mihalik SJ, Kim DG, et al. (2000). "The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase.". J. Biol. Chem. 275 (21): 15605–8. doi:10.1074/jbc.C000015200. PMID 10749848.
Steinberg SJ, Wang SJ, McGuinness MC, Watkins PA (1999). "Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein.". Mol. Genet. Metab. 68 (1): 32–42. doi:10.1006/mgme.1999.2883. PMID 10479480.
Watkins PA, Pevsner J, Steinberg SJ (2000). "Human very long-chain acyl-CoA synthetase and two human homologs: initial characterization and relationship to fatty acid transport protein.". Prostaglandins Leukot. Essent. Fatty Acids 60 (5-6): 323–8. PMID 10471116.
Hirsch D, Stahl A, Lodish HF (1998). "A family of fatty acid transporters conserved from mycobacterium to man.". Proc. Natl. Acad. Sci. U.S.A. 95 (15): 8625–9. PMID 9671728.