SLC25A12

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Solute carrier family 25 (mitochondrial carrier, Aralar), member 12
Identifiers
Symbol(s) SLC25A12; ARALAR; ARALAR1
External IDs OMIM: 603667 MGI: 1926080 HomoloGene: 48235
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 8604 78830
Ensembl ENSG00000115840 ENSMUSG00000027010
Uniprot O75746 Q8BH59
Refseq NM_003705 (mRNA)
NP_003696 (protein)		 NM_172436 (mRNA)
NP_766024 (protein)
Location Chr 2: 172.35 - 172.46 Mb Chr 2: 71.07 - 71.17 Mb
Pubmed search [1] [2]

Solute carrier family 25 (mitochondrial carrier, Aralar), member 12, also known as SLC25A12, is a human gene.[1]


[edit] See also

[edit] References

  1. ^ Entrez Gene: SLC25A12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12.

[edit] Further reading

  • del Arco A, Satrústegui J (1998). "Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain.". J. Biol. Chem. 273 (36): 23327–34. PMID 9722566. 
  • Kobayashi K, Sinasac DS, Iijima M, et al. (1999). "The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein.". Nat. Genet. 22 (2): 159–63. doi:10.1038/9667. PMID 10369257. 
  • Crackower MA, Sinasac DS, Lee JR, et al. (2000). "Assignment of the SLC25A12 gene coding for the human calcium-binding mitochondrial solute carrier protein aralar to human chromosome 2q24.". Cytogenet. Cell Genet. 87 (3-4): 197–8. PMID 10702666. 
  • Sanz R, del Arco A, Ayuso C, et al. (2000). "Assignment of the calcium-binding mitochondrial carrier Aralar1 gene (SLC25A12) to human chromosome band 2q31 by in situ hybridization.". Cytogenet. Cell Genet. 89 (3-4): 143–4. PMID 10965105. 
  • Palmieri L, Pardo B, Lasorsa FM, et al. (2001). "Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria.". EMBO J. 20 (18): 5060–9. doi:10.1093/emboj/20.18.5060. PMID 11566871. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Ramoz N, Reichert JG, Smith CJ, et al. (2004). "Linkage and association of the mitochondrial aspartate/glutamate carrier SLC25A12 gene with autism.". The American journal of psychiatry 161 (4): 662–9. PMID 15056512. 
  • Rubi B, del Arco A, Bartley C, et al. (2005). "The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.". J. Biol. Chem. 279 (53): 55659–66. doi:10.1074/jbc.M409303200. PMID 15494407. 
  • Rabionet R, McCauley JL, Jaworski JM, et al. (2006). "Lack of association between autism and SLC25A12.". The American journal of psychiatry 163 (5): 929–31. doi:10.1176/appi.ajp.163.5.929. PMID 16648338. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
  • Hong CJ, Liou YJ, Liao DL, et al. (2007). "Association study of polymorphisms in the mitochondrial aspartate/glutamate carrier SLC25A12 (aralar) gene with schizophrenia.". Prog. Neuropsychopharmacol. Biol. Psychiatry 31 (7): 1510–3. doi:10.1016/j.pnpbp.2007.07.010. PMID 17693006. 
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v • d • e
Membrane proteins, carrier proteins: membrane transport proteins
ABC-transporter
A1, A2, A3, A4, A7, A8, A12, B1

B2-3, B2, B3, B4, B5, B6, B7, B9, B11

C1, C2, C3, C4, C5, C6, C8, C8-9, C10, C13, C11

D1, D2, D3, D4, E1, F1, F2

G1, G2, G4, Sterolin (G5, G8)
Solute carrier
1A1-7, 1A1, 1A2, 1A3, 1A4, 1A5, 2A1, 2A2, 2A3, 2A4, 2A5, 2A6, 2A8, 2A9, 2A10, 2A12, 3A1, 3A2, 4A1, 4A2, 4A3, 4A4, 4A5, 4A7, 4A8, 4A11, 5A1-2, 5A1, 5A3, 5A5, 5A8, 6A1, 6A2, 6A3, 6A4, 6A5, 6A8, 6A9, 6A19, 7A1, 7A2, 7A3, 7A4, 7A5, 7A7, 7A8, 7A9, 7A11, 8A1-3, 9A1, 9A2, 9A3, 9A3R1, 9A3R2, 9A5, 9A6, 9A8, 10A1, 10A2, 10A3, 10A7, 11A1, 11A2, 11A3, 12A1-2, 12A3, 12A4, 12A5, 12A6, 12A7, 14A1, 13A3, 14A2, 15A1, 15A2, 16A1, 16A2, 16A3, 16A4, 17A1, 17A5, 17A6-8, 17A7, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 20A1, 20A2, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 22A7, 22A9, 22A11, 22A12, 22A18, 23A1, 23A2, 24A1-2, 24A5, 25A1, 25A3, 25A4, 25A4-6, 25A8, 25A10, 25A11, 25A12, 25A13, 25A14, 25A15, 25A17, 25A19, 25A20, 25A27, 25A31, 25A37, 25A39, 26A2, 26A3, 26A4, 26A5, 26A6, 26A7, 26A8, 27A1, 27A2, 27A3, 27A4, 28A1, 28A2, 29A1, 29A2, 29A4, 30A4, 30A7, 30A8, 31A1, 31A2, 32A1, 34A1, 34A2, 34A3, 35A1, 35A2, 35B2, 35B4, 35C1, 36A1, 37A4, 38A2, 38A3, 39A1, 39A2, 39A3, 39A4, 39A6, 39A7, 40A1, 43A1 44A1, 44A2, 44A4, 45A2, O1A2, O1B1, O1B3, O2B1, O431, O4A1
Monosaccharide
Other