SLC17A1

From Wikipedia, the free encyclopedia

Solute carrier family 17 (sodium phosphate), member 1

Identifiers

SLC17A1; MGC126794; MGC126796; NAPI-1; NPT-1; NPT1

External IDs

OMIM: 182308 MGI: 103209 HomoloGene: 48324

Gene ontology
Molecular Function:	• transporter activity • phosphate transmembrane transporter activity • symporter activity • sodium-dependent phosphate transmembrane transporter activity • sodium ion binding
Cellular Component:	• membrane fraction • integral to plasma membrane • membrane • integral to membrane
Biological Process:	• transport • ion transport • sodium ion transport • phosphate transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005074 (mRNA)
NP_005065 (protein)

NM_009198 (mRNA)
NP_033224 (protein)

Location

Chr 6: 25.89 - 25.94 Mb

Chr 13: 23.88 - 23.9 Mb

Pubmed search

[1]

[2]

Solute carrier family 17 (sodium phosphate), member 1, also known as SLC17A1, is a human gene.^[1]

[edit] See also

Solute carrier family

[edit] References

^ Entrez Gene: SLC17A1 solute carrier family 17 (sodium phosphate), member 1.

[edit] Further reading

Miyamoto K, Tatsumi S, Sonoda T, et al. (1995). "Cloning and functional expression of a Na(+)-dependent phosphate co-transporter from human kidney: cDNA cloning and functional expression.". Biochem. J. 305 ( Pt 1): 81–5. PMID 7826357.
Chong SS, Kristjansson K, Zoghbi HY, Hughes MR (1994). "Molecular cloning of the cDNA encoding a human renal sodium phosphate transport protein and its assignment to chromosome 6p21.3-p23.". Genomics 18 (2): 355–9. doi:10.1006/geno.1993.1476. PMID 8288239.
Li H, Xie Z (1997). "Molecular cloning of two rat Na+/Pi cotransporters: evidence for differential tissue expression of transcripts.". Cell. Mol. Biol. Res. 41 (5): 451–60. PMID 8867793.
Taketani Y, Miyamoto K, Chikamori M, et al. (1998). "Characterization of the 5' flanking region of the human NPT-1 Na+/phosphate cotransporter gene.". Biochim. Biophys. Acta 1396 (3): 267–72. PMID 9545579.
Totaro A, Roetto A, Rommens JM, et al. (1998). "Generation of a transcription map of a 1 Mbase region containing the HFE gene (6p22).". Eur. J. Hum. Genet. 6 (2): 105–13. doi:10.1038/sj.ejhg.5200162. PMID 9781053.
Uchino H, Tamai I, Yamashita K, et al. (2000). "p-aminohippuric acid transport at renal apical membrane mediated by human inorganic phosphate transporter NPT1.". Biochem. Biophys. Res. Commun. 270 (1): 254–9. doi:10.1006/bbrc.2000.2407. PMID 10733936.
Soumounou Y, Gauthier C, Tenenhouse HS (2001). "Murine and human type I Na-phosphate cotransporter genes: structure and promoter activity.". Am. J. Physiol. Renal Physiol. 281 (6): F1082–91. PMID 11704559.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gisler SM, Pribanic S, Bacic D, et al. (2004). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells.". Kidney Int. 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. PMID 14531806.

This membrane protein-related article is a stub. You can help Wikipedia by expanding it.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

v • d • e Membrane proteins, carrier proteins: membrane transport proteins

ABC-transporter	A1, A2, A3, A4, A7, A8, A12, B1 B2-3, B2, B3, B4, B5, B6, B7, B9, B11 C1, C2, C3, C4, C5, C6, C8, C8-9, C10, C13, C11 D1, D2, D3, D4, E1, F1, F2 G1, G2, G4, Sterolin (G5, G8)

Solute carrier	1A1-7, 1A1, 1A2, 1A3, 1A4, 1A5, 2A1, 2A2, 2A3, 2A4, 2A5, 2A6, 2A8, 2A9, 2A10, 2A12, 3A1, 3A2, 4A1, 4A2, 4A3, 4A4, 4A5, 4A7, 4A8, 4A11, 5A1-2, 5A1, 5A3, 5A5, 5A8, 6A1, 6A2, 6A3, 6A4, 6A5, 6A8, 6A9, 6A19, 7A1, 7A2, 7A3, 7A4, 7A5, 7A7, 7A8, 7A9, 7A11, 8A1-3, 9A1, 9A2, 9A3, 9A3R1, 9A3R2, 9A5, 9A6, 9A8, 10A1, 10A2, 10A3, 10A7, 11A1, 11A2, 11A3, 12A1-2, 12A3, 12A4, 12A5, 12A6, 12A7, 14A1, 13A3, 14A2, 15A1, 15A2, 16A1, 16A2, 16A3, 16A4, 17A1, 17A5, 17A6-8, 17A7, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 20A1, 20A2, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 22A7, 22A9, 22A11, 22A12, 22A18, 23A1, 23A2, 24A1-2, 24A5, 25A1, 25A3, 25A4, 25A4-6, 25A8, 25A10, 25A11, 25A12, 25A13, 25A14, 25A15, 25A17, 25A19, 25A20, 25A27, 25A31, 25A37, 25A39, 26A2, 26A3, 26A4, 26A5, 26A6, 26A7, 26A8, 27A1, 27A2, 27A3, 27A4, 28A1, 28A2, 29A1, 29A2, 29A4, 30A4, 30A7, 30A8, 31A1, 31A2, 32A1, 34A1, 34A2, 34A3, 35A1, 35A2, 35B2, 35B4, 35C1, 36A1, 37A4, 38A2, 38A3, 39A1, 39A2, 39A3, 39A4, 39A6, 39A7, 40A1, 43A1 44A1, 44A2, 44A4, 45A2, O1A2, O1B1, O1B3, O2B1, O431, O4A1

Monosaccharide	GLUT1, GLUT2, GLUT3, GLUT4, GLUT5, GLUT6, GLUT8, GLUT9

Other	Amino acid (CD98) - Fatty acid (CD36) - Ion channels - Ion pumps - Mitochondrial membrane transport protein - Neurotransmitter transport proteins - Nuclear (Importin, Karyopherin)