SLC12A7
From Wikipedia, the free encyclopedia
Solute carrier family 12 (potassium/chloride transporters), member 7
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Identifiers | ||||||||||||||
Symbol(s) | SLC12A7; DKFZP434F076; KCC4 | |||||||||||||
External IDs | OMIM: 604879 MGI: 1342283 HomoloGene: 21312 | |||||||||||||
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RNA expression pattern | ||||||||||||||
Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 10723 | 20499 | ||||||||||||
Ensembl | ENSG00000113504 | ENSMUSG00000017756 | ||||||||||||
Uniprot | Q9Y666 | Q3TB23 | ||||||||||||
Refseq | NM_006598 (mRNA) NP_006589 (protein) |
NM_011390 (mRNA) NP_035520 (protein) |
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Location | Chr 5: 1.1 - 1.17 Mb | Chr 13: 74.2 - 74.28 Mb | ||||||||||||
Pubmed search | [1] | [2] |
Solute carrier family 12 (potassium/chloride transporters), member 7, also known as SLC12A7, is a human gene.[1]
[edit] See also
[edit] References
[edit] Further reading
- Mount DB, Mercado A, Song L, et al. (1999). "Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family.". J. Biol. Chem. 274 (23): 16355–62. PMID 10347194.
- Mercado A, Song L, Vazquez N, et al. (2000). "Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.". J. Biol. Chem. 275 (39): 30326–34. doi: . PMID 10913127.
- Hattori A, Okumura K, Nagase T, et al. (2001). "Characterization of long cDNA clones from human adult spleen.". DNA Res. 7 (6): 357–66. PMID 11214971.
- Boettger T, Hübner CA, Maier H, et al. (2002). "Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4.". Nature 416 (6883): 874–8. doi: . PMID 11976689.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Bräuer M, Frei E, Claes L, et al. (2003). "Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.". Am. J. Physiol., Cell Physiol. 285 (1): C22–30. doi: . PMID 12637262.
- Karadsheh MF, Byun N, Mount DB, Delpire E (2004). "Localization of the KCC4 potassium-chloride cotransporter in the nervous system.". Neuroscience 123 (2): 381–91. PMID 14698746.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi: . PMID 14702039.
- Shen MR, Lin AC, Hsu YM, et al. (2004). "Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells.". J. Biol. Chem. 279 (38): 40017–25. doi: . PMID 15262997.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi: . PMID 15489334.
- Hsu YM, Chou CY, Chen HH, et al. (2007). "IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness.". J. Cell. Physiol. 210 (3): 626–36. doi: . PMID 17133354.