SLAMF1

From Wikipedia, the free encyclopedia


Signaling lymphocytic activation molecule family member 1
Identifiers
Symbol(s) SLAMF1; CD150; CDw150; SLAM
External IDs OMIM: 603492 MGI1351314 HomoloGene48162
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 6504 27218
Ensembl ENSG00000117090 ENSMUSG00000015316
Uniprot Q13291 Q18PK4
Refseq NM_003037 (mRNA)
NP_003028 (protein)
NM_013730 (mRNA)
NP_038758 (protein)
Location Chr 1: 158.84 - 158.88 Mb Chr 1: 173.6 - 173.64 Mb
Pubmed search [1] [2]

Signaling lymphocytic activation molecule family member 1, also known as SLAMF1, is a human gene.[1]

SLAMF1 has also recently has been designated CD150 (cluster of differentiation 150).


[edit] References

[edit] Further reading

  • Cocks BG, Chang CC, Carballido JM, et al. (1995). "A novel receptor involved in T-cell activation.". Nature 376 (6537): 260-3. doi:10.1038/376260a0. PMID 7617038. 
  • Punnonen J, Cocks BG, Carballido JM, et al. (1997). "Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes.". J. Exp. Med. 185 (6): 993-1004. PMID 9091591. 
  • Sayos J, Wu C, Morra M, et al. (1998). "The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM.". Nature 395 (6701): 462-9. doi:10.1038/26683. PMID 9774102. 
  • Mikhalap SV, Shlapatska LM, Berdova AG, et al. (1999). "CDw150 associates with src-homology 2-containing inositol phosphatase and modulates CD95-mediated apoptosis.". J. Immunol. 162 (10): 5719-27. PMID 10229804. 
  • Li SC, Gish G, Yang D, et al. (2000). "Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A.". Curr. Biol. 9 (23): 1355-62. PMID 10607564. 
  • Rogge L, Bianchi E, Biffi M, et al. (2000). "Transcript imaging of the development of human T helper cells using oligonucleotide arrays.". Nat. Genet. 25 (1): 96-101. doi:10.1038/75671. PMID 10802665. 
  • Tatsuo H, Ono N, Tanaka K, Yanagi Y (2000). "SLAM (CDw150) is a cellular receptor for measles virus.". Nature 406 (6798): 893-7. doi:10.1038/35022579. PMID 10972291. 
  • Lewis J, Eiben LJ, Nelson DL, et al. (2001). "Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.". Clin. Immunol. 100 (1): 15-23. doi:10.1006/clim.2001.5035. PMID 11414741. 
  • Morra M, Simarro-Grande M, Martin M, et al. (2001). "Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients.". J. Biol. Chem. 276 (39): 36809-16. doi:10.1074/jbc.M101305200. PMID 11477068. 
  • Kruse M, Meinl E, Henning G, et al. (2001). "Signaling lymphocytic activation molecule is expressed on mature CD83+ dendritic cells and is up-regulated by IL-1 beta.". J. Immunol. 167 (4): 1989-95. PMID 11489980. 
  • Bleharski JR, Niazi KR, Sieling PA, et al. (2001). "Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines.". J. Immunol. 167 (6): 3174-81. PMID 11544303. 
  • Morra M, Lu J, Poy F, et al. (2001). "Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.". EMBO J. 20 (21): 5840-52. doi:10.1093/emboj/20.21.5840. PMID 11689425. 
  • Howie D, Simarro M, Sayos J, et al. (2002). "Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation.". Blood 99 (3): 957-65. PMID 11806999. 
  • Murabayashi N, Kurita-Taniguchi M, Ayata M, et al. (2002). "Susceptibility of human dendritic cells (DCs) to measles virus (MV) depends on their activation stages in conjunction with the level of CDw150: role of Toll stimulators in DC maturation and MV amplification.". Microbes Infect. 4 (8): 785-94. PMID 12270725. 
  • Li C, Iosef C, Jia CY, et al. (2003). "Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors.". J. Biol. Chem. 278 (6): 3852-9. doi:10.1074/jbc.M206649200. PMID 12458214. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Hahm B, Arbour N, Naniche D, et al. (2003). "Measles virus infects and suppresses proliferation of T lymphocytes from transgenic mice bearing human signaling lymphocytic activation molecule.". J. Virol. 77 (6): 3505-15. PMID 12610126. 
  • Del Valle JM, Engel P, Martín M (2003). "The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2).". J. Biol. Chem. 278 (19): 17430-7. doi:10.1074/jbc.M301569200. PMID 12621057. 
  • Ferrand V, Li C, Romeo G, Yin L (2003). "Absence of SLAM mutations in EBV-associated lymphoproliferative disease patients.". J. Med. Virol. 70 (1): 131-6. doi:10.1002/jmv.10373. PMID 12629654. 
  • Laaksonen K, Junikka M, Lahesmaa R, et al. (2004). "In vitro allergen-induced mRNA expression of signaling lymphocytic activation molecule by PBMC of patients with allergic rhinitis is increased during specific pollen immunotherapy.". J. Allergy Clin. Immunol. 112 (6): 1171-7. doi:10.1016/j.jaci.2003.08.043. PMID 14657878.