SL2 RNA

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SL2 RNA
Template:Abbreviation
Type: Gene;
2° structure: Published; PubMed; Moxon SJ
Seed alignment: Moxon SJ
Avg length: 109.0 nucleotides
Avg identity: 73%

SL2 RNA is a non-coding RNA involved in trans splicing in lower eukaryotes. Trans-splicing is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an intra-molecular reaction which precisely joins exons derived from separately transcribed RNAs.[1] Approximately 25% of C. elegans genes are organised into polycistronic transcription units and the presence of SL2 on an mRNA is an indication the the gene is in an operon.[2]

[edit] References

  1. ^ Dassanayake, RS; Chandrasekharan NV, Karunanayake EH (2001). "Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay". Gene 269: 185–193. doi:10.1016/S0378-1119(01)00438-3. PMID 11376950. 
  2. ^ Evans, D; Blumenthal T (2000). "trans splicing of polycistronic Caenorhabditis elegans pre-mRNAs: analysis of the SL2 RNA". Mol Cell Biol 20: 6659–6667. doi:10.1128/MCB.20.18.6659-6667.2000. PMID 10958663. 

[edit] External links