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SL2 RNA |
|
Type: |
Gene; |
2° structure: |
Published; PubMed; Moxon SJ |
Seed alignment: |
Moxon SJ |
Avg length: |
109.0 nucleotides |
Avg identity: |
73% |
|
SL2 RNA is a non-coding RNA involved in trans splicing in lower eukaryotes. Trans-splicing is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an intra-molecular reaction which precisely joins exons derived from separately transcribed RNAs.[1] Approximately 25% of C. elegans genes are organised into polycistronic transcription units and the presence of SL2 on an mRNA is an indication the the gene is in an operon.[2]
[edit] References
- ^ Dassanayake, RS; Chandrasekharan NV, Karunanayake EH (2001). "Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay". Gene 269: 185–193. doi:10.1016/S0378-1119(01)00438-3. PMID 11376950.
- ^ Evans, D; Blumenthal T (2000). "trans splicing of polycistronic Caenorhabditis elegans pre-mRNAs: analysis of the SL2 RNA". Mol Cell Biol 20: 6659–6667. doi:10.1128/MCB.20.18.6659-6667.2000. PMID 10958663.
[edit] External links