SKIV2L2

From Wikipedia, the free encyclopedia

Superkiller viralicidic activity 2-like 2 (S. cerevisiae)

Identifiers

SKIV2L2; Dob1; KIAA0052; MGC142069; Mtr4

External IDs

MGI: 1919448 HomoloGene: 6257

Gene ontology
Molecular Function:	• nucleotide binding • nucleic acid binding • protein binding • ATP binding • ATP-dependent helicase activity • hydrolase activity
Cellular Component:	• nucleus • spliceosome
Biological Process:	• mRNA processing • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_015360 (mRNA)
NP_056175 (protein)

NM_028151 (mRNA)
NP_082427 (protein)

Location

Chr 5: 54.64 - 54.76 Mb

Chr 13: 113.99 - 114.05 Mb

Pubmed search

[1]

[2]

Superkiller viralicidic activity 2-like 2 (S. cerevisiae), also known as SKIV2L2, is a human gene.^[1]

[edit] References

^ Entrez Gene: SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae).

[edit] Further reading

Nomura N, Nagase T, Miyajima N, et al. (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 1 (5): 223–9. PMID 7584044.
Brouwer R, Allmang C, Raijmakers R, et al. (2001). "Three novel components of the human exosome.". J. Biol. Chem. 276 (9): 6177–84. doi:10.1074/jbc.M007603200. PMID 11110791.
Chen CY, Gherzi R, Ong SE, et al. (2002). "AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.". Cell 107 (4): 451–64. PMID 11719186.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. PMID 11790298.
Raijmakers R, Noordman YE, van Venrooij WJ, Pruijn GJ (2002). "Protein-protein interactions of hCsl4p with other human exosome subunits.". J. Mol. Biol. 315 (4): 809–18. doi:10.1006/jmbi.2001.5265. PMID 11812149.
Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.". RNA 8 (4): 426–39. PMID 11991638.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus.". Mol. Biol. Cell 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.". Genomics 83 (1): 153–67. PMID 14667819.
Lin Z, Crockett DK, Lim MS, Elenitoba-Johnson KS (2004). "High-throughput analysis of protein/peptide complexes by immunoprecipitation and automated LC-MS/MS.". J Biomol Tech 14 (2): 149–55. PMID 14676314.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Nagahama M, Yamazoe T, Hara Y, et al. (2006). "The AAA-ATPase NVL2 is a component of pre-ribosomal particles that interacts with the DExD/H-box RNA helicase DOB1.". Biochem. Biophys. Res. Commun. 346 (3): 1075–82. doi:10.1016/j.bbrc.2006.06.017. PMID 16782053.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
Schilders G, van Dijk E, Pruijn GJ (2007). "C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.". Nucleic Acids Res. 35 (8): 2564–72. doi:10.1093/nar/gkm082. PMID 17412707.
Yang CT, Hindes AE, Hultman KA, Johnson SL (2007). "Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.". PLoS Genet. 3 (6): e88. doi:10.1371/journal.pgen.0030088. PMID 17542649.